ArticleMovement disorders clinical practice2026
Ocular Motor Abnormalities in Functional Neurological Disorder: A Video-Oculography Study.
Article in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Altered Saccades, Blink and Pupil Responses in Functional Motor Disorder: New Insight Into Neurobiological Mechanisms.European journal of neurology · 2026Article
- Visuo-Vestibular Virtual Reality-Based Training for People with Stroke: A Feasibility Study.Healthcare (Basel, Switzerland) · 2026Article
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14 authors.
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Abstract
backgroundFunctional neurological disorders (FND) can include various sensory, motor or cognitive symptoms. Eye movement recordings, measured through video-oculography, could serve as biomarkers for characterizing these dysfunctions in FND.
objectiveTo identify oculomotor patterns that may help to support a positive diagnosis of FND.
methodsWe conducted a retrospective analysis of video-oculography recordings performed between 2011 and 2023 in 149 patients with FND, focusing on horizontal and vertical prosaccades, smooth pursuit, and antisaccades. These data were compared with those obtained from 132 age and gender-matched healthy volunteers and 43 patients diagnosed with multiple sclerosis (MS).
resultsFND patients exhibited significantly increased mean saccade latencies in both horizontal and vertical prosaccade tasks compared to controls (t-test, P < 0.0001). Additionally, variability in horizontal and upward saccade latency was substantially greater in the FND group than in the control and MS groups (P < 0.0001). Vertical saccades in FND patients were hypometric (P < 0.0001) with increased variability of upward saccade amplitude (P < 0.0001). Both MS and FND patients had higher antisaccade error rates than controls (P < 0.0001).
conclusionThese findings suggest that video oculography may be useful in understanding the pathophysiology of FND and highlight its potential as a complementary tool to support diagnostic reasoning in complex clinical presentations.
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