Evidence map›Paper›PMID 41090512›Full record

ArticleJournal of cosmetic dermatology2025

The Safety and Efficacy of the Mono-Bi CrossLIFT Technique Utilizing Capacitive-Coupled Sequential Monopolar and Bipolar Pulsed Radiofrequency for Simultaneous Facial Skin Tightening and Contouring: A Clinical Case Series.

Kentaro Oku

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kentaro OkuHILLS GRACE CLINIC, Yokohama, Japan.ORCID https://orcid.org/0009-0009-9308-7523

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNoninvasive facial rejuvenation techniques that emphasize skin tightening and contouring continue to gain popularity due to their minimally invasive nature and favorable clinical outcomes. Recent technological advancements, such as capacitive-coupled sequential monopolar and bipolar pulsed radiofrequency (SMBPRF), enable simultaneous targeted collagen remodeling within the dermis and contraction of subdermal fibrous tissues.

objectiveTo comprehensively evaluate the clinical safety and efficacy of the Mono-Bi CrossLIFT Technique utilizing SMBPRF for simultaneous facial skin tightening and contour improvement.

methodsSixteen healthy adults (aged 36-59 years, Fitzpatrick skin types II-IV) with mild to moderate facial skin laxity and sagging were enrolled in this study. Each participant underwent a single treatment session of SMBPRF using the Mono-Bi CrossLIFT Technique. Quantitative assessments, including skin tightening distances (mm) and changes in lower facial tissue thickness (mm), were performed at baseline and 24 weeks post-treatment using high-resolution three-dimensional imaging. Clinical efficacy was evaluated using the Global Aesthetic Improvement Scale (GAIS) by both an independent dermatologist and the subjects themselves. Pain levels and adverse events were also recorded throughout the study period.

resultsAll 16 subjects completed the study. Statistically significant improvements in both skin tightening and facial contouring were observed in 15 subjects. The mean skin tightening distance was 0.82 ± 0.36 mm (p = 3.528 × 10

conclusionMono-Bi CrossLIFT Technique utilizing SMBPRF demonstrated significant safety and bidirectional improvement, supporting its clinical utility as a noninvasive method for comprehensive facial rejuvenation.

Indexed as

Cosmetic TechniquesPulsed Radiofrequency TreatmentRejuvenationRhytidoplastySkin AgingAdultFaceFemaleHumansMaleMiddle AgedPatient SatisfactionSkinTreatment Outcomefacial contouringfacial rejuvenationMono‐Bi CrossLIFT Techniqueradiofrequency (RF)sequential monopolar–bipolar radiofrequency (SMBPRF)skin tightening

Identifiers

PMID41090512
PMCPMC12522179

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.