Evidence map›Paper›PMID 41090440›Full record

ArticleFuture oncology (London, England)2025

Nab-paclitaxel vs paclitaxel liposome for advanced breast cancer: real-world efficacy and safety analysis.

Meng-Ting Li, Ji-Sheng Chen

Abstract readComparative Study
In one paragraph

Article in Future oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Meng-Ting LiDepartment of Pharmacy, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Guangzhou, Guangdong, China.ORCID 0000-0002-4185-821X
Ji-Sheng ChenKey Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.ORCID 0000-0003-3514-9086

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe incidence and mortality rates of breast cancer are increasing globally every year. Paclitaxel is one of the most widely used chemotherapeutic agents for solid tumors. Conducting studies in the real world is of great clinical importance and research value. This study evaluates the application and efficacy of different types of paclitaxel in patients with advanced breast cancer.

methodsA retrospective cohort study was conducted. For effectiveness, we focused on objective response rate (ORR), Disease Control Rate (DCR), and progression-free survival (PFS). For safety, we focused on the incidence of adverse events (ARE). The Kaplan-Meier survival function, and COX proportional risk regression model were used for data processing and analysis.

resultsNab-paclitaxel DCR was significantly higher than paclitaxel liposome (

conclusionNab-paclitaxel or paclitaxel liposomes remain significantly effective in patients with advanced breast cancer who have failed first or multiline therapy. Nab-paclitaxel is superior to paclitaxel liposome in efficacy evaluation, paclitaxel liposome is superior to nab-paclitaxel in survival outcome.

Indexed as

AlbuminsAntineoplastic Agents, PhytogenicBreast NeoplasmsPaclitaxelAdultAgedFemaleHumansKaplan-Meier EstimateLiposomesMiddle AgedNeoplasm StagingRetrospective StudiesTreatment Outcome130-nm albumin-bound paclitaxelAlbuminsAntineoplastic Agents, PhytogenicLiposomesPaclitaxeladvanced breast canceradverse effectspaclitaxel injectionpaclitaxel liposomesreal-world study

Identifiers

PMID41090440
PMCPMC12622329

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.