Evidence map›Paper›PMID 41090433›Full record

ArticlePest management science2026

Bed bug preferences for host odor or aggregation odor are differentially modulated by physiological state in various odorscapes.

Ayako Wada-Katsumata, Christopher C Hayes, Charles A Kwadha, Alexander Ko, Coby Schal

Abstract read
In one paragraph

Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Ayako Wada-KatsumataDepartment of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC, USA.ORCID https://orcid.org/0000-0002-2895-1102
Christopher C HayesDepartment of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC, USA.ORCID https://orcid.org/0000-0003-3868-4922
Charles A KwadhaDepartment of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC, USA.
Alexander KoEnvu, Cary, NC, USA.
Coby SchalDepartment of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC, USA.ORCID https://orcid.org/0000-0001-7195-6358

Funding

A North Carolina State University Global One Health Academy Postdoctoral 257367-25145Department of the Army, U.S. Army Contracting Command, Aberdeen Proving Ground, Natick Contracting Division, Ft Detrick MD W911QY1910011Research Capacity Fund (HATCHU.S. Department of Agriculture National Institute of Food and AgricultureU.S. Department of Agriculture Southern IPM Center (S24-058)U.S. Department of Housing and Urban Development Healthy Homes program NCHHU0053-19U.S. Department of Housing and Urban Development Healthy Homes program NCHHU0081-24
6 · The paper itself

Abstract

backgroundBed bugs live in an ecologically and spatially restricted indoor habitat comprised of overlapping aggregation and host odors, and they traverse relatively short distances between blood-hosts and aggregation sites. Although many studies demonstrated aggregation or host odor preference respectively, the modulation of bed bug preferences between these divergent odors is poorly understood. Given the recurrent transitions of bed bugs between replete and hungry states, we evaluated the effects of six odorscapes containing aggregation and host skin odors on bed bug preferences.

resultsHunger state modulated odor preference for aggregation and foraging in all tested odorscapes. Aggregation odor attracted both fed and unfed bed bugs. Host skin odor attracted unfed bed bugs but repelled recently fed bed bugs and the addition of carbon dioxide to host odor enhanced the behavioral responses. These findings suggest that orientation to aggregation sites in fed bed bugs is driven by two distinct odor-processing mechanisms for attractant and aversive odors. Unfed bed bugs discriminate between two attractive odors-aggregation and host odors-but host odor predominates over aggregation odor in driving their orientation behavior.

conclusionUnderstanding the dynamic switching of odor preferences during the blood digestion cycle will guide the implementation of chemical lures in integrated pest management. Host odors alone and their co-emission with aggregation pheromone repelled fed bed bugs from traps. Conversely, unfed bed bugs had a strong preference for host odor emitted either alone or with aggregation odor. Therefore, the independent use of either host or aggregation odor lures and their co-emission from the same trap should be carefully considered. © 2025 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

BedbugsOdorantsAnimalsBehavior, AnimalFemaleInsect ControlMalePheromonesPheromonesaggregationbed bugsCimex lectulariushost‐seekingodor preferenceodorscape

Identifiers

PMID41090433
PMCPMC12790647

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.