Evidence map›Paper›PMID 41090426›Full record

ArticleInternational journal of fertility & sterility2025

Endometrial Steroid Receptor Dysregulation and Its Association with Vitamin D, AMH, and Inflammation in Recurrent Implantation Failure: A Case-Control Study.

Rahim Rostami, Jamileh Jahanbakhsh, Elmira Mahdinia, Azadeh Rezaei, Sahar Yarahmadi, Nafiseh Omodiani, Afsaneh Tehranian, Soudabeh Fallah

Abstract read
In one paragraph

Article in International journal of fertility & sterility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rahim RostamiDepartment of Clinical Biochemistry, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Jamileh JahanbakhshInfertility Ward, Arash Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Elmira MahdiniaDepartment of Clinical Biochemistry, Faculty of Medicine, Golestan University of Medical Sciences, Tehran, Iran.
Azadeh RezaeiDepartment of Clinical Biochemistry, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Sahar YarahmadiDepartment of Clinical Biochemistry, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Nafiseh OmodianiDepartment of Clinical Biochemistry, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Afsaneh TehranianDepartment of Gynecology and Obstetrics, Arash Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran. Email: tehrania@sina.tums.ac.ir.
Soudabeh FallahDepartment of Clinical Biochemistry, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran. Email: Fallah.s@iums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Defects in endometrial receptivity are significant factors in infertility and recurrent implantation failure (RIF) during Materials and Methods: This case-control study was conducted in Tehran from June 2021 to December 2023, involving 50 fertile women as controls and 50 women with unexplained RIF referred to the RIF Medical Center at Arash Hospital. Blood samples and endometrial biopsies were collected at the day of the LH surge was LH 0. The expression levels of estrogen receptors ( Results: Women with RIF exhibited significantly higher Conclusion: The study links endometrial PGR-B expression and vitamin D3 levels to decidualization and inflammation regulation. It suggests that infertility in women with RIF may stem from elevated ESR-α, increased inflammation, and reduced

Indexed as

Estrogen ReceptorsFemale InfertilityInflammationProgesterone Receptor-BVitamin D3

Identifiers

PMID41090426
PMCPMC12530196

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.