ArticleInternational journal of fertility & sterility2025
Combination of Vitamin D Plus Probiotic Affects Hormonal, and Inflammatory Markers in Women with Polycystic Ovary Syndrome Undergoing
Article in International journal of fertility & sterility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Influence of vitamin D supplementation on ovarian reserve as reflected by anti-Müllerian hormone levels: a meta-analysis of randomized controlled trials.Frontiers in endocrinology · 2026Pooled it
- Probiotic-Mediated Vitamin D Supplementation Improves the Gut Microbiota and Vitamin D Receptor Composition in Obese Rats.Food science & nutrition · 2026Article
- Precision Nutrition in Type 2 Diabetes Prevention Through Molecular Nutrigenomic and Epigenetic Modulation of Insulin Signaling and Glucose Metabolism.International journal of molecular sciences · 2026Review
- Microecological modulators-new perspectives for treating sex hormone disorders.Frontiers in microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study aimed to evaluate the effects of vitamin D and probiotic supplements on anti-Mullerian hormone (AMH), glycemic control, inflammatory markers, and Materials and Methods: A randomized, double-blind, placebo-controlled trial was conducted with 120 women aged 30-45 years, diagnosed with PCOS and undergoing IVF. Participants were divided into four groups (30 each): daily 4,000 IU vitamin D, probiotic (1.8×10 Results: After 8 weeks, the combination group showed significant reductions in insulin levels (-0.33 ± 0.37 vs. -0.14 ± 0.29, -0.11 ± 0.04, -0.02 ± 0.36 μIU/mL, P=0.020), insulin resistance (-0.07 ± 0.09 vs. -0.03 ± 0.07, -0.03 ± 0.09, -0.07 ± 0.09, P=0.024), and increased insulin sensitivity (+0.001 ± 0.001 vs. +0.0006 ± 0.001, +0.0005 ± 0.002, +0.00004 ± 0.001, P=0.034) compared to other groups. The combination also led to a significant reduction in high-sensitivity C-reactive protein (hs-CRP) levels (-0.18 ± 0.22 vs. -0.07 ± 0.17, -0.08 ± 0.15, +0.04 ± 0.18, P=0.001). No significant changes were observed in plasma total nitrite, fasting glucose, and AMH levels. There was a notable decrease in Conclusion: The combined supplementation of vitamin D and probiotics over 8 weeks improved insulin function, hs-CRP levels, and
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.