Evidence map›Paper›PMID 41090372›Full record

ArticleUrogynecology (Philadelphia, Pa.)2026

Chemodenervation Use for Overactive Bladder in Female Medicare Beneficiaries.

Nancy E Ringel, Charles D Scales, Cassie B Ford, C Emi Bretschneider, Ekene Enemchukwu, Victoria L Handa

Abstract read
In one paragraph

Article in Urogynecology (Philadelphia, Pa.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Health Disparities and Overactive Bladder: Bridging the Gap.Current bladder dysfunction reports · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nancy E RingelDepartment of Obstetrics, Gynecology, & Reproductive Sciences, Division of Urogynecology & Reconstructive Pelvic Surgery, Yale School of Medicine, New Haven, CT.ORCID 0000-0001-6063-699
Charles D ScalesDepartments of Urology and Population Health Sciences, Duke Clinical Research Institute, Duke University School of Medicine.
Cassie B FordDepartment of Population Health, Duke University, Durham, NC.
C Emi BretschneiderDivision of Urogynecology and Reconstructive Pelvic Surgery, Northwestern University, Chicago, IL.
Ekene EnemchukwuDepartment of Urology, Stanford University Medical Center, Palo Alto, CA.
Victoria L HandaDepartment of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD.

Funding

Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
UrogynCREST ProgramR25HD094667 · NICHD · DUKE UNIVERSITY · PI Cindy Amundsen · 2019 to 2026
$1.2M
NCATS NIH HHS KL2 TR001862NICHD NIH HHS R25 HD094667
6 · The paper itself

Abstract

importanceOnly a fraction of women with overactive bladder (OAB) receive effective treatment for this condition; inequities in access to OAB care must be understood.

objectiveThe objective of this study was to explore features associated with intradetrusor chemodenervation treatment for OAB among female Medicare beneficiaries from different racial and ethnic groups. STUDY

designThis was a retrospective cohort study of females ≥65 years old from the Center for Medicare & Medicaid Services' 5% Limited Data Set with a diagnosis of OAB between 2012 and 2020. The cumulative incidence of beneficiaries who received intradetrusor chemodenervation within 5 years following OAB diagnosis was compared between race and ethnicity groups. Cox regression analysis was performed to determine predictors for the likelihood of intradetrusor chemodenervation treatment and to adjust for potential confounders.

resultsIn total, 232,366 females with a new OAB diagnosis were identified. The cumulative incidence of intradetrusor chemodenervation treatment within 5 years of OAB diagnosis was low at 1.4%, with lower rates among Asian (0.6%), Black (0.7%), Hispanic (0.7%), and Other groups (0.9%) ( P < 0.001). After adjustments, non-White race and Hispanic ethnicity (Asian: adjusted hazard ratio [aHR] 0.51, 95% CI: 0.33-0.80; Black: aHR 0.56, 95% CI: 0.45-0.69; Hispanic: aHR 0.62, 95% CI: 0.40-0.96; Other: aHR 0.58, 95% CI: 0.37-0.91) were associated with a lower relative hazard of receiving intradetrusor chemodenervation.

conclusionsOverall utilization of intradetrusor chemodenervation was low in this national cohort. Women from non-White racial and ethnic groups had lower rates of utilization compared with White women. Further research should evaluate barriers patients face in accessing this effective OAB treatment and explore potential interventions that facilitate access to care.

Indexed as

Healthcare DisparitiesMedicareUrinary Bladder, OveractiveAgedAged, 80 and overEthnicityFemaleHumansRetrospective StudiesUnited States

Identifiers

PMID41090372
PMCPMC12766854

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.