ReviewThe Japanese dental science review2025
Optimizing titanium dioxide-functionalized polymethyl methacrylate (PMMA-TiO₂) for dental applications: A systematic review on physicochemical parameters and antimicrobial outcomes.
Review in The Japanese dental science review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Role of Surface Topography in Bacterial Adhesion to Amorphous TiODentistry journal · 2026Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Polymethyl methacrylate (PMMA) resins are widely used in dental prostheses due to their excellent physical, mechanical, and aesthetic properties. However, their susceptibility to microbial colonization can compromise oral and systemic health. Titanium dioxide (TiO₂), with its photocatalytic activity, has gained attention for its antimicrobial potential. This systematic review investigates how the physicochemical properties of TiO₂ affect its antimicrobial efficacy in PMMA-TiO₂ composites, aiming to optimize their performance and clinical effectiveness. Methods: PubMed, Embase, Scopus, ScienceDirect, Web of Science, Google Scholar, and ProQuest were searched in October 2024. Articles were selected in two stages by two blinded researchers based on predefined eligibility criteria. Risk of bias was assessed using the RobDEMAT tool. Results: A comprehensive search identified 1464 articles, which were screened by title and abstract according to inclusion criteria. Of the 28 studies selected for full-text review, 24 were included in this systematic review, all of which were in vitro studies. Due to the high heterogeneity of the selected studies, which prevented statistical analysis of the data, a descriptive analysis was performed. Conclusions: The balance between concentration, size, crystallinity, and surface morphology can enhance TiO₂ photocatalytic activity and reduce microbial adhesion. Synthesis and functionalization strategies can overcome limitations, expanding the clinical applicability, efficiency, and durability of PMMA-TiO₂ composites.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.