Evidence map›Paper›PMID 41090154›Full record

ArticleMedComm2025

cZFP609 Tethering BiP Alleviates Cartilage Degradation in Osteoarthritis via Remedying Aberrant ER-Mitochondrial Contacts.

Yu Song, Jun-Long Luo, Fan Zhang, Jie Shi, Shuai Du, Hai-Bin Jiang, Wen-Di Zhang, Si-Ying Chen, Dan-Dan Zhang, Peng Kong and 3 more

Abstract read
In one paragraph

Article in MedComm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yu SongDepartment of Biochemistry and Molecular Biology College of Basic Medicine Key Laboratory of Neural and Vascular Biology of Ministry of Education Key Laboratory of Vascular Biology of Hebei Province Hebei Medical University Shijiazhuang China.
Jun-Long LuoDepartment of Orthopaedic Surgery Institute of Biomechanical Science and Biomechanical Key Laboratory of Hebei Province Third Hospital of Hebei Medical University Shijiazhuang China.
Fan ZhangDepartment of Biochemistry and Molecular Biology College of Basic Medicine Key Laboratory of Neural and Vascular Biology of Ministry of Education Key Laboratory of Vascular Biology of Hebei Province Hebei Medical University Shijiazhuang China.
Jie ShiDepartment of Biochemistry and Molecular Biology College of Basic Medicine Key Laboratory of Neural and Vascular Biology of Ministry of Education Key Laboratory of Vascular Biology of Hebei Province Hebei Medical University Shijiazhuang China.
Shuai DuDepartment of Orthopaedic Surgery Institute of Biomechanical Science and Biomechanical Key Laboratory of Hebei Province Third Hospital of Hebei Medical University Shijiazhuang China.
Hai-Bin JiangDepartment of Biochemistry and Molecular Biology College of Basic Medicine Key Laboratory of Neural and Vascular Biology of Ministry of Education Key Laboratory of Vascular Biology of Hebei Province Hebei Medical University Shijiazhuang China.
Wen-Di ZhangDepartment of Biochemistry and Molecular Biology College of Basic Medicine Key Laboratory of Neural and Vascular Biology of Ministry of Education Key Laboratory of Vascular Biology of Hebei Province Hebei Medical University Shijiazhuang China.
Si-Ying ChenDepartment of Biochemistry and Molecular Biology College of Basic Medicine Key Laboratory of Neural and Vascular Biology of Ministry of Education Key Laboratory of Vascular Biology of Hebei Province Hebei Medical University Shijiazhuang China.
Dan-Dan ZhangDepartment of Biochemistry and Molecular Biology College of Basic Medicine Key Laboratory of Neural and Vascular Biology of Ministry of Education Key Laboratory of Vascular Biology of Hebei Province Hebei Medical University Shijiazhuang China.
Peng KongDepartment of Biochemistry and Molecular Biology College of Basic Medicine Key Laboratory of Neural and Vascular Biology of Ministry of Education Key Laboratory of Vascular Biology of Hebei Province Hebei Medical University Shijiazhuang China.
Yuan GaoDepartment of Biochemistry and Molecular Biology College of Basic Medicine Key Laboratory of Neural and Vascular Biology of Ministry of Education Key Laboratory of Vascular Biology of Hebei Province Hebei Medical University Shijiazhuang China.
Mei HanDepartment of Biochemistry and Molecular Biology College of Basic Medicine Key Laboratory of Neural and Vascular Biology of Ministry of Education Key Laboratory of Vascular Biology of Hebei Province Hebei Medical University Shijiazhuang China.
Han LiDepartment of Orthopaedic Surgery Institute of Biomechanical Science and Biomechanical Key Laboratory of Hebei Province Third Hospital of Hebei Medical University Shijiazhuang China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular dysfunction is implicated in the pathogenesis of osteoarthritis (OA). Herein, we utilized smooth muscle specific human

Indexed as

binding immunoglobulin proteincZFP609ferroptosisOsteoarthritis

Identifiers

PMID41090154
PMCPMC12516089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.