Evidence map›Paper›PMID 41090135›Full record

ReviewFrontiers in medicine2025

Addressing the current challenges in the clinical application of AI-based Radiomics for cancer imaging.

Yongzhong Xu, Yunxin Li, Feng Wang, Yafei Zhang, Delong Huang

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yongzhong XuDepartment of Imaging, Yantaishan Hospital, Yantai, China.
Yunxin LiDepartment of Imaging, Yantaishan Hospital, Yantai, China.
Feng WangDepartment of Imaging, Yantaishan Hospital, Yantai, China.
Yafei ZhangDepartment of Imaging, Yantaishan Hospital, Yantai, China.
Delong HuangDepartment of Imaging, Yantaishan Hospital, Yantai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of artificial intelligence (AI) into Radiomics has transformed cancer imaging by enabling advanced predictive modeling, improved diagnostic accuracy, and personalized treatment strategies. However, the clinical application of AI-based Radiomics faces significant challenges that hinder its widespread adoption. Intrinsic limitations, such as limited datasets, data heterogeneity, and the lack of interpretability in AI models, compromise reliability and generalizability. Practical challenges, including integration into rigid clinical workflows, infrastructural constraints, regulatory barriers, and clinician training gaps, further complicate implementation. Addressing these barriers requires coordinated efforts to establish standardized imaging protocols, foster multi-institutional collaborations, and develop centralized repositories of diverse datasets. In addition, challenges programs for healthcare professionals and regulatory reforms are essential to build trust and streamline adoption. Future research should prioritize enhancing AI interpretability, conducting longitudinal studies to assess clinical impact, and incorporating patient-centered approaches to align AI models with precision medicine objectives. By overcoming these challenges, AI-based Radiomics can advance cancer imaging, improve patient outcomes, and contribute to a new era in personalized cancer care.

Indexed as

artificial intelligencecancer imagingclinical integrationdiagnostic accuracymachine learningprecision medicineRadiomics

Identifiers

PMID41090135
PMCPMC12515897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.