Evidence map›Paper›PMID 41090075›Full record

ArticleFrontiers in veterinary science2025

Improving heat resilience in fattening rabbits: nutritional strategies for mitigation via regulating blood physiology, inflammation and antioxidant pathways.

Hadeel Kamil Khaleel, Sameh A Abdelnour, Raha Osailan, Khaled H El-Kholy, Ehab El-Haroun, Hamdy A El-Nagar, Sara T Mehilp, Ali A El-Raghi, Mahmoud A Hassan, Mahmoud Moustafa and 1 more

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hadeel Kamil KhaleelDepartment of Basic Science, College of Dentistry, Al-Iraqia University, Baghdad, Iraq.
Sameh A AbdelnourDepartment of Animal Production, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.
Raha OsailanBiology Department, Faculty of Science, Taibah University, Yanbu, Saudi Arabia.
Khaled H El-KholyDepartment of Animal, Poultry, and Fish Production, Faculty of Agriculture, Damietta University, Damietta, Egypt.
Ehab El-HarounDepartment of Integrative Agriculture, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, United Arab Emirates.
Hamdy A El-NagarAnimal Production Research Institute, Agriculture Research Centre, Ministry of Agriculture, Giza, Egypt.
Sara T MehilpDepartment of Animal, Poultry, and Fish Production, Faculty of Agriculture, Damietta University, Damietta, Egypt.
Ali A El-RaghiDepartment of Animal, Poultry, and Fish Production, Faculty of Agriculture, Damietta University, Damietta, Egypt.
Mahmoud A HassanAnimal Production Research Institute, Agriculture Research Centre, Ministry of Agriculture, Giza, Egypt.
Mahmoud MoustafaDepartment of Biology, College of Science, King Khalid University, Abha, Saudi Arabia.
Ibrahim T El-RatelDepartment of Animal, Poultry, and Fish Production, Faculty of Agriculture, Damietta University, Damietta, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Global heat waves increasingly threaten food security, by reducing food supplies and negatively impacting livestock health. This research investigates nutritional interventions aimed at improving rabbit productivity and health, with a particular focus on mitigating the effects of heat stress (HS) conditions. Hence, this research investigates the potential of various feed additives to enhance growth, immunity, and overall health in environmentally stressed growing rabbits by reducing inflammatory and apoptotic signaling. Materials and method: To investigate the effects of various supplements on rabbits under natural heat stress, 150 rabbits were divided into five groups with 30 rabbits each. The groups were given a control diet or supplemented with 1 ml of silver nanoparticles (AgNPs), 0.2 g of chitosan, 100 mg of silymarin, or a combination of all three for 8 weeks. The Temperature-Humidity Index (THI) was calculated to be 30.04, indicating severe heat stress. Results: Results indicated that all feed supplements significantly improved live body weight and average daily gain ( Conclusion: Therefore, incorporating mixture of natural molecules (1 ml AgNPs, 0.2 chitosan, and 100 mg silymarin) into the diet provides a sustainable and promising solution for rabbit production to combat heat stress associated with global climate change.

Indexed as

Apoposisfeed additivesinflammationrabbitsilver nanoparticles

Identifiers

PMID41090075
PMCPMC12515684

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.