Evidence map›Paper›PMID 41089927›Full record

ArticleJournal of spine surgery (Hong Kong)2025

Giant calcified lumbar disc herniation in post-operative adjacent segment degeneration: a case report.

Harold Keyserling, Yi Zhang, Stephen Skirboll, Raymond A Sobel, Byung C Yoon

Abstract readCase Reports
In one paragraph

Article in Journal of spine surgery (Hong Kong), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Harold KeyserlingDepartment of Radiology, VA Palo Alto Healthcare System, Palo Alto, CA and Stanford University School of Medicine, Stanford, CA, USA.
Yi ZhangDepartment of Neurosurgery, VA Palo Alto Healthcare System, Palo Alto, CA and Stanford University School of Medicine, Stanford, CA, USA.
Stephen SkirbollDepartment of Neurosurgery, VA Palo Alto Healthcare System, Palo Alto, CA and Stanford University School of Medicine, Stanford, CA, USA.
Raymond A SobelDepartment of Pathology, VA Palo Alto Healthcare System, Palo Alto, CA and Stanford University School of Medicine, Stanford, CA, USA.
Byung C YoonDepartment of Radiology, VA Palo Alto Healthcare System, Palo Alto, CA and Stanford University School of Medicine, Stanford, CA, USA.ORCID https://orcid.org/0000-0003-2929-5677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Giant, calcified disc herniation is a rare type of intervertebral disc calcification and herniation where a large calcified, herniated disc occupies more than 40% of the spinal canal. Cases of giant, calcified disc herniations have been reported primarily in the thoracic spine in adults. They are associated with more symptomatic disc disease and can pose surgical challenges. However, little is known about their occurrence in the lumbar spine, especially in association with prior spine surgeries. The aim of this case report is to describe clinical findings and management of rare, giant, calcified disc herniation presenting as adjacent level degeneration in the lumbar spine. Case Description: A 75-year-old man with several previous lumbar spine surgeries, including posterior instrumented fusion at L3-S1, presented with a 5-week history of progressive bilateral lower extremity weakness. Lumbar spine magnetic resonance imaging (MRI) and computed tomography (CT) revealed a large, calcified intraspinal mass in the right paracentral region at L2-L3, adjacent to the prior surgical levels. It resulted in severe narrowing of the right lateral recess. This lesion was new when compared to the lumbar spine MRI performed 6 months prior. The lesion was surgically resected without complications, and the pathology revealed a degenerating disc with bone fragments and calcifications. Conclusions: This case demonstrates an unusual presentation of a giant, calcified disc herniation in the lumbar spine as a component of adjacent segment degeneration in a patient with prior lumbar spine surgeries. The case illustrates the dynamic nature of intervertebral disc herniations and calcifications as well as management considerations.

Indexed as

adjacent segment degenerationcase reportdisc calcificationgiant disc herniationSpine surgery

Identifiers

PMID41089927
PMCPMC12516573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.