ArticleJournal of health economics and outcomes research2025
Impact of Body Mass Index and Comorbidities on Health-Related Quality of Life and Work Productivity in People With Overweight or Obesity: A Survey-Based Study in the United Kingdom.
Article in Journal of health economics and outcomes research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Obesity, Employment, and Economic Productivity in Europe: A Systematic Literature Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Employee perceptions and experiences with tirzepatide treatment for obesity or overweight in the US: Insights from the PERCEPTIONS Survey.Obesity pillars · 2026Article
- Psychometric Validation of the Weight and Emotions Scale (WES) in Adults with Obesity or Overweight.Advances in therapy · 2026Article
- Ten-year cardiometabolic progression and health-related quality of life in individuals with isolated abdominal obesity.BMC public health · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The prevalence and socioeconomic impact of obesity are increasing in the United Kingdom; however, the effects of body mass index (BMI) and comorbidities on health-related quality of life (HRQoL) and work productivity in people living with overweight or obesity (PLwO) have not been fully described. Objective: To assess self-reported HRQoL and work productivity in PLwO in the United Kingdom, grouped by BMI and presence of cardiovascular and/or metabolic (CVM) comorbidities. Methods: Data used were from the Adelphi Obesity Disease Specific Programme™, a real-world cross-sectional survey (October 2023-April 2024). Physicians reported demographic and clinical characteristics for PLwO on a weight management program who were ≥18 years old and had current or previous BMI ≥30 kg/m2, or ≥27 kg/m2 with ≥1 weight-related comorbidity. The same PLwO completed the 36-item Short-Form Health Survey version 2 (SF-36v2) and Work Productivity and Activity Impairment: Specific Health Problem (WPAI:SHP) questionnaire. Results: Physicians provided data for 904 PLwO, of whom 119 completed the survey questionnaires. Mean age for PLwO was 51.7 years, 54% were women, the majority were White (69%), and 70% had ≥1 CVM comorbidity. SF-36v2 physical functioning scores were lower with higher BMI (P < .05). Scores for physical functioning, role limitations due to physical problems, bodily pain, general health, vitality, and the physical component summary were lower ( Discussion: Increasing BMI may be linked to lower physical functioning in PLwO. Comorbidities were associated with reductions in HRQoL, with different domains affected depending on the type of comorbidity. These comorbidities were also associated with impaired work productivity. Conclusion: The presence of comorbidities, along with BMI, are important considerations for managing obesity. Reducing the prevalence of overweight or obesity is likely to benefit both individuals and wider society.
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