ArticleJournal of multidisciplinary healthcare2025
Global Research Trends in Childhood Asthma and the Microbiome: A Bibliometric Analysis of 2000 to 2024.
Article in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Multi-omics analysis: Gut microbial metabolites in ovarian lesions.The Journal of international medical research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study systematically maps the global publications on childhood asthma and the microbiome from 2000 to 2024, quantifying publication output, collaboration networks, thematic evolution, and research gaps to guide future basic and translational work. Methods: On 30 March 2025, the Web of Science Core Collection was searched. English articles and reviews published between 2000 and 2024 were retained, yielding 2,537 records. Annual output was summarised with Microsoft Excel 2021, while VOSviewer 1.6.20, CiteSpace 6.4 R1, Scimago Graphica, and Charticulator were employed to visualise country, institution, author, and journal networks as well as keyword co-occurrence, bursts, and thematic clusters. Results: Annual publications rose exponentially, peaking at 225 papers in 2022; the United States led in volume (802 papers), citations (48,856), and H-index (105), partnering most closely with the United Kingdom, while China's fast growing output has yet to match Western citation impact. Copenhagen University, Ludwig-Maximilians-Universität Munich, and authors such as Erika von Mutius and Hans Bisgaard occupied central positions in collaboration and co-citation networks. The high frequency and centrality of the keywords "gut microbiota", "early life" and "regulatory T cells" highlight the pivotal role of the early-life gut-lung axis, while keyword burst analysis shows that research has shifted from the hygiene-hypothesis phase toward short-chain fatty acids, multi-omics integration and personalised micro-ecological interventions. Conclusion: Over the past quarter century, research on childhood asthma and the microbiome has progressed from macro level epidemiology to multi omics mechanism and is now entering a precision medicine phase. Future priorities include longitudinal birth cohort multi omics, targeted restoration of key taxa or metabolites, and expanded participation of low and middle income regions through strengthened international collaboration to reduce the global burden of childhood asthma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.