ReviewJournal of multidisciplinary healthcare2025
Nursing Interventions in Palliative Care for Advanced Dementia: A Systematic Review of Symptom, Relief, Comfort, and Caregiver Support.
Review in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Individuals with advanced dementia often endure high symptom burden and receive limited specialized palliative care. Nurses play a central role in delivering end-of-life care, yet the impact of nurse-led interventions remains underexplored. This review synthesizes available evidence on nursing-led approaches, with a focus on symptom relief, patient comfort, and caregiver support. Methods: A systematic review was conducted in accordance with PRISMA 2020 guidelines. Four databases (PubMed, Embase, CINAHL, and Cochrane Library) were searched for studies published between January 2015 and March 2025. Eligible studies included randomized controlled trials (RCTs), cluster RCTs, and non-randomized studies evaluating nurse-led palliative interventions in institutional or community dementia settings. Risk of bias was assessed using Cochrane RoB 2.0 and ROBINS-I tools. Data extraction focused on intervention types, delivery modes, nurse training, and clinical outcomes. Results: Twenty-three studies from 12 countries were included (8 cluster RCTs, 9 individual RCTs, 6 non-randomized trials). Nurse-led programs improved care planning (≥75% documentation rates), reduced caregiver decisional conflict (20-30%), and enhanced communication quality (by up to 20 percentage points). Pain detection increased by 41%, with validated tools reducing pain scores by up to 30%. Psychosocial therapies reduced agitation by up to 25% and improved care cooperation. Multicomponent models decreased emergency visits and improved transitions, with over 40% increases in advance directive completion. Risk of bias varied by design and domain. Conclusion: Nurse-led palliative care interventions show consistent benefits in communication, symptom control, and caregiver support. However, evidence on long-term caregiver outcomes is limited, and heterogeneity in design and measurement limits comparability. Standardized, scalable models are needed to fully integrate nursing-led approaches into palliative dementia care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.