Evidence map›Paper›PMID 41089724›Full record

ArticleMaterials today. Bio2025

Injectable magnetic hydrogel induces multi-programmed cell death and deep tumor regression in magnetic hyperthermia therapy in hepatocellular carcinoma.

Linxue Zhang, Xing He, Hongyu Zhu, Qi Sun, Yu Liu, Lin Huang, Tianlong Wen, Jianfu Li, Zhongwen Lan, Zhong Yu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Linxue ZhangThe Sichuan Provincial Key Laboratory for Human Disease Gene Study and Center for Medical Genetics, Department of Laboratory Medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610072, China.
Xing HeThe Sichuan Provincial Key Laboratory for Human Disease Gene Study and Center for Medical Genetics, Department of Laboratory Medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610072, China.
Hongyu ZhuSchool of Materials and Energy, University of Electronic Science and Technology of China, 611731, Chengdu, China.
Qi SunSchool of Materials and Energy, University of Electronic Science and Technology of China, 611731, Chengdu, China.
Yu LiuSchool of Materials and Energy, University of Electronic Science and Technology of China, 611731, Chengdu, China.
Lin HuangSchool of Electronic Science and Technology, University of Electronic Science and Technology of China, China.
Tianlong WenSchool of Electronic Science and Technology, University of Electronic Science and Technology of China, China.
Jianfu LiSchool of Life Science and Technology, University of Electronic Science and Technology of China, China.
Zhongwen LanSchool of Materials and Energy, University of Electronic Science and Technology of China, 611731, Chengdu, China.
Zhong YuSchool of Materials and Energy, University of Electronic Science and Technology of China, 611731, Chengdu, China.
Zhenglin YangThe Sichuan Provincial Key Laboratory for Human Disease Gene Study and Center for Medical Genetics, Department of Laboratory Medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610072, China.
Kun JiaSchool of Materials and Energy, University of Electronic Science and Technology of China, 611731, Chengdu, China.
Ke SunSchool of Materials and Energy, University of Electronic Science and Technology of China, 611731, Chengdu, China.
Ziyan WangThe Sichuan Provincial Key Laboratory for Human Disease Gene Study and Center for Medical Genetics, Department of Laboratory Medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610072, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) remains global health concern due to complex pathogenic mechanism and lack of effective therapeutic drugs. The magnetic hyperthermia therapy (MHT) appears as the promising and safe strategy during the recent exploration of new technology for cancer treatment. Herein, we reported an injectable and magnetic-hydrogel-construct-based thermal regression agent mPEG-

Indexed as

Cysteine metabolismHepatocellular carcinomaMagnetic hyperthermia therapymPEG-b-PLV-Fe3O4Redox homeostasis

Identifiers

PMID41089724
PMCPMC12517087

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.