ArticleMedical journal of the Islamic Republic of Iran2025
Dietary Intakes of Omega-3, Omega-6 and Fiber and Risk of Rectal Cancer: A Case-Control Study.
Article in Medical journal of the Islamic Republic of Iran, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Rectal cancer (RC) is one of the most commonly occurring cancers in Iran in recent years. Dietary intakes of Omega-3 (ω-3), Omega-6 (ω-6), and fiber have been thought to diminish the risk of RC. Therefore, this study was conducted to evaluate the association of dietary ω-3, ω-6, and fiber with the risk of RC. Methods: In this case-control study, dietary intakes of ω-3 and ω-6 were estimated using a 148-item food frequency questionnaire (FFQ) between 363 people (162 cases, 201 control) aged 20-80 years old. Cases were patients with RC, and controls were healthy people. Odds ratios (OR) and 95% confidence intervals (CI) were assessed using logistic regression models. Results: According to the multiple logistic regression model with the backward method, dietary fiber intake was inversely associated with RC as a protective factor (OR=0.3; 95%CI= 0.1-0.9; Conclusion: Although no association between ω-3 and ω-6 intake was observed with the risk of RC, adequate daily intake of dietary fiber may protect us against RC risk.
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