Evidence map›Paper›PMID 41089608›Full record

ArticleMedical journal of the Islamic Republic of Iran2025

Validation of Kazakh and Russian Generic Drug Questionnaire.

Zhandulla Nakipov, Ulugbek Musaev, Indira Smagylova, Karlygash Raissova, Zhanar Bukeyeva, Assiya K Turgambayeva, Gaukhar Dauletova, Zakira Kerimbayeva, Dinara Kaliyeva, Nabil Joseph Awadalla

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Article in Medical journal of the Islamic Republic of Iran, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Zhandulla NakipovDepartment of Public Health and Management, NJSC «Astana Medical University», Astana City, Republic of Kazakhstan.
Ulugbek MusaevDepartment of "Public Health, Healthcare Management and Physical Culture", Dental Institute, Tashkent city, Republic of Uzbekistan.
Indira SmagylovaClinical Diagnostic Center, SME on REM "Multidisciplinary City Children's Hospital No.2", Astana city, Republic of Kazakhstan.
Karlygash RaissovaResearch School, NJSC «Astana Medical University», Astana city, Republic of Kazakhstan.
Zhanar BukeyevaDeputy of the Research Institute of Preventive Medicine named after Academician E.D. Dalenov, NJSC "Astana Medical University", Astana city, Republic of Kazakhstan.
Assiya K TurgambayevaDepartment of Public Health and Management, NJSC «Astana Medical University», Astana City, Republic of Kazakhstan.ORCID https://orcid.org/0000-0002-2300-0105
Gaukhar DauletovaDepartment of Public Health and Management, NJSC «Astana Medical University», Astana City, Republic of Kazakhstan.
Zakira KerimbayevaDepartment of Public Health and Management, NJSC «Astana Medical University», Astana City, Republic of Kazakhstan.
Dinara KaliyevaPublic Association Farmideya-Kazakhstan, Pharmacovigilance Manager , Astana city, Republic of Kazakhstan.
Nabil Joseph AwadallaDepartment of Community Medicine, Mansoura Faculty of Medicine, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The widespread use of generic drugs (GDs) represents a key strategy for reducing medication costs for patients and the healthcare sector. Promoting the rational use of GDs requires a clear understanding of physicians' knowledge and attitudes, assessed through reliable and culturally validated instruments. This study aimed to adapt and validate the Kazakh and Russian versions of a standardized questionnaire designed to evaluate physicians' knowledge and attitudes toward GDs. The validated tool is intended to support future research, educational programs, and policy efforts aimed at enhancing the rational prescription and utilization of GD in the Republic of Kazakhstan. Methods: The questionnaire underwent a standardized forward-backward translation process in accordance with internationally accepted guidelines for cross-cultural adaptation of survey instruments. A pilot study was subsequently conducted among physicians in Shymkent, Republic of Kazakhstan, to evaluate its clarity and applicability in real-world conditions. To examine the psychometric properties of the Kazakh and Russian versions, Confirmatory Factor Analysis (CFA) was carried out using the Structural Equation Modeling (SEM) module in Jamovi software. In addition, descriptive statistics, standardized factor loadings, factor covariances, and model fit indices were calculated to assess the validity and internal structure of the instrument. Results: Confirmatory Factor Analysis (CFA) supported the hypothesized two-factor model comprising the latent constructs "Information" and "Attitude" in both the Kazakh and Russian versions of the questionnaire. The majority of items demonstrated statistically significant standardized factor loadings, with several exceeding the recommended threshold of 0.70, indicating strong associations with their respective latent variables. The estimated correlation between the two factors was moderate in the Kazakh version (r = 0.599) and strong in the Russian version (r = 0.780), suggesting a meaningful conceptual relationship between physicians' knowledge and attitudes toward generic drugs. Conclusion: The psychometric evaluation confirmed that the questionnaire has an adequate internal structure, with most items showing significant factor loadings and acceptable model fit. These findings support its use as a reliable tool for assessing physicians' awareness and attitudes toward generic medicines in Kazakhstan.

Indexed as

AttitudeGeneric DrugsKazakhKnowledgePhysiciansRussianValidation

Identifiers

PMID41089608
PMCPMC12516443

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