Evidence map›Paper›PMID 41089546›Full record

ArticleJournal of experimental orthopaedics2025

Effects of a novel externally rotated trochlear design on patellofemoral kinematics in total knee arthroplasty: A cadaveric study.

Tommaso Bonanzinga, Alberto Favaro, Luca Bertolino, Gabriele Fassina, Bharat Sharma, Francesco Iacono

Abstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tommaso BonanzingaIRCCS Humanitas Research Hospital Rozzano Milan Italy.ORCID https://orcid.org/0000-0003-2861-4699
Alberto FavaroIRCCS Humanitas Research Hospital Rozzano Milan Italy.ORCID https://orcid.org/0000-0002-9143-0393
Luca BertolinoHumanitas University Pieve Emanuele Milan Italy.ORCID https://orcid.org/0009-0004-0122-7036
Gabriele FassinaDepartment of Electronics, Information and Bioengineering Politecnico di Milano Milano Italy.ORCID https://orcid.org/0009-0006-6916-3432
Bharat SharmaDakshas Foundation Hyderabad India.
Francesco IaconoIRCCS Humanitas Research Hospital Rozzano Milan Italy.ORCID https://orcid.org/0000-0001-6825-2851

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate whether a novel femoral component with a trochlear sulcus externally rotated (EXT) by 3°, mimicking the natural relationship between the posterior condylar axis (PCA) and epicondylar axis (EA), improves patellofemoral (PF) kinematics in total knee arthroplasty (TKA) by more closely replicating native patellar motion. Methods: A cadaveric study was conducted on 12 lower limbs from six fresh-frozen hemi-body specimens. After acquiring native knee kinematics using an optical navigation system, each knee underwent TKA with two prosthetic designs: a standard (STD) implant and an EXT variant with a 3° lateralized trochlear groove. Patellar kinematics were evaluated in flexion-extension movements, and quantified via root mean square error, correlation coefficient and normalized range relative to native conditions. Statistical comparisons were performed using the Wilcoxon signed-rank test. Results: Patellar flexion was similar across native and prosthetic conditions. However, the STD design showed significantly lower patellar misalignment than the EXT in terms of patellar shift ( Conclusions: Although theoretically promising, the EXT trochlear design did not lead to improved replication of native PF kinematics. The findings suggest that trochlear sulcus lateralization alone is insufficient to restore physiological patellar tracking. Level of Evidence: Level V, cadaveric study.

Indexed as

kneepatellofemoral jointpatellofemoral kinematicspatellofemoral trackingtotal knee arthroplasty

Identifiers

PMID41089546
PMCPMC12516919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.