Evidence map›Paper›PMID 41089442›Full record

ReviewChemical science2025

Gas-mediated reinforcement of cancer therapies: emerging strategies and future perspectives.

Fang Yuan, Lu Wang, Lulu Ning, Jianjian Zhang, Yuan Guo

Abstract readReview
In one paragraph

Review in Chemical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Emerging Nanoplatforms are Effective Against Tumor Hypoxia.International journal of nanomedicine · 2026
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fang YuanKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University Xi'an 710127 P. R. China zhangjj@nwu.edu.cn guoyuan@nwu.edu.cn.
Lu WangKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University Xi'an 710127 P. R. China zhangjj@nwu.edu.cn guoyuan@nwu.edu.cn.
Lulu NingShaanxi Provincial Key Laboratory of Papermaking Technology and Specialty Paper Development, College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science & Technology Xi'an 710021 P. R. China ninglulu@sust.edu.cn.
Jianjian ZhangKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University Xi'an 710127 P. R. China zhangjj@nwu.edu.cn guoyuan@nwu.edu.cn.ORCID https://orcid.org/0000-0002-5220-1280
Yuan GuoKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University Xi'an 710127 P. R. China zhangjj@nwu.edu.cn guoyuan@nwu.edu.cn.ORCID https://orcid.org/0000-0003-2081-7264

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer therapy has made notable progress in moving towards more precise, intelligent and personalized treatment modes. However, current approaches such as chemotherapy, phototherapy, sonodynamic therapy, and immune therapy still suffer from limitations, hindering their application in clinical practice. Gasotransmitters have long been recognized as key regulators in cancer pathology, and the development of novel therapeutic agents with gas-releasing ability aiming to establish new therapeutic modes has garnered considerable attention. In this perspective, we aim to summarize the critical roles of gaseous molecules in cancer biology and their potential mechanisms for enhancing the efficacy of dominant treatment modalities. We also provide insights into recent advances in integrating gas therapy with conventional treatments to overcome current challenges and improve therapeutic outcomes, ultimately paving the way for the development of next-generation treatment paradigms.

Identifiers

PMID41089442
PMCPMC12516763

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.