ReviewBurns & trauma2025
Metal semiconductor materials in bone diseases: properties, applications, and future perspectives.
Review in Burns & trauma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Engineering Nanoscale Frontiers: Valve Metal Oxide Nanostructures From Fundamentals to Multifunctional Biomedical Applications.Chemical record (New York, N.Y.) · 2026Review
- Evolutionary applications of electrical stimulation in bone repair: bibliometric trends and temporal dynamics.EFORT open reviews · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of bone tissue engineering is to develop innovative biomaterials and stimulation strategies to promote bone regeneration. Bioelectric materials play a crucial role in this domain owing to their inspiration of the inherent piezoelectric properties of bone. This review explores the progress made in utilizing metal semiconductor materials for bone tissue engineering, focusing on their operating mechanisms, various material classifications, and the ways they foster bone regeneration. First, the working principles of metal semiconductor materials are discussed, with an emphasis on the importance of bioelectric phenomena in regulating cell behavior. Owing to their roles in mimicking the electrophysiological microenvironment to promote bone regeneration, we highlight various types of metal semiconductor materials, such as metallic semiconductor materials, piezoelectric materials, and conductive biomaterials. Personalized and specific materials, including conductive smart scaffolds, modified implant surfaces, and those that target bone tissues, promote osseointegration and exert antibacterial properties, serving diverse applications in bone tissue engineering. Additionally, to improve implant biocompatibility and osseointegration, the use of metal semiconductor materials in the design of orthopedic implants has shown promising clinical application prospects. Finally, looking forward to the future applications of metal semiconductor materials in bone engineering, integrating multiple functions, personalized medicine, and biodegradable materials, as well as the application of nanotechnology and 3D printing techniques, may arise to satisfy clinical requirements. This review also presents the biological characteristics of metal semiconductor materials and their recent applications in treating bone diseases, while also discussing innovative concepts for their design and development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.