Evidence map›Paper›PMID 41089376›Full record

ArticleBrain communications2025

Single-nucleus RNA sequencing: immature excitatory neurons and transformed glia build human BRAF

Silvia Cases-Cunillera, Philipp Müller, Ashley J van Waardenberg, Susanne Schoch, Gilles Huberfeld, Anke Höllig, Daniel Delev, Motaz Hamed, Albert J Becker, Karen M J van Loo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Ras-MAPK somatic variants in mesial temporal lobe epilepsy.Current opinion in genetics & development · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Silvia Cases-CunilleraUniversité Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), ISERM U1266, Neuronal Signaling in Epilepsy and Glioma, Paris 75014, France.ORCID https://orcid.org/0000-0002-9156-4754
Philipp MüllerInstitute for Cellular Neurosciences II, Medical Faculty, University of Bonn, Bonn 53127, Germany.ORCID https://orcid.org/0009-0001-4001-8542
Ashley J van Waardenbergi-Synapse, Cairns 4870, Australia.
Susanne SchochInstitute for Cellular Neurosciences II, Medical Faculty, University of Bonn, Bonn 53127, Germany.
Gilles HuberfeldUniversité Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), ISERM U1266, Neuronal Signaling in Epilepsy and Glioma, Paris 75014, France.
Anke HölligDepartment of Neurosurgery, RWTH Aachen University Hospital, Aachen 52074, Germany.
Daniel DelevDepartment of Neurosurgery, RWTH Aachen University Hospital, Aachen 52074, Germany.
Motaz HamedDepartment of Neurosurgery, University Hospital Bonn, Bonn 53127, Germany.
Albert J BeckerInstitute for Cellular Neurosciences II, Medical Faculty, University of Bonn, Bonn 53127, Germany.
Karen M J van LooDepartment of Neurosurgery, RWTH Aachen University Hospital, Aachen 52074, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gangliogliomas are glioneuronal neoplasms, generally with a benign evolution, accounting for the most common tumours in patients with long-term pharmacoresistant epilepsy.

Indexed as

glutamatergicimmature excitatory neuronsneuronal development

Identifiers

PMID41089376
PMCPMC12516308

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.