Evidence map›Paper›PMID 41089326›Full record

ArticleVirus evolution2025

Phylogenetic analysis of pigeon paramyxovirus type 1 detected in the British Isles between 1983 and 2023.

Alexander M P Byrne, Benjamin C Mollett, Ian H Brown, Joe James, Ashley C Banyard, Craig S Ross

Abstract read
In one paragraph

Article in Virus evolution, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander M P ByrneDepartment of Virology, Animal and Plant Health Agency (APHA-Weybridge), Woodham Lane, Addlestone, Surrey KT15 3NB, United Kingdom.
Benjamin C MollettDepartment of Virology, Animal and Plant Health Agency (APHA-Weybridge), Woodham Lane, Addlestone, Surrey KT15 3NB, United Kingdom.ORCID https://orcid.org/0000-0003-1608-0191
Ian H BrownDepartment of Virology, Animal and Plant Health Agency (APHA-Weybridge), Woodham Lane, Addlestone, Surrey KT15 3NB, United Kingdom.ORCID https://orcid.org/0000-0003-3909-1301
Joe JamesDepartment of Virology, Animal and Plant Health Agency (APHA-Weybridge), Woodham Lane, Addlestone, Surrey KT15 3NB, United Kingdom.
Ashley C BanyardDepartment of Virology, Animal and Plant Health Agency (APHA-Weybridge), Woodham Lane, Addlestone, Surrey KT15 3NB, United Kingdom.
Craig S RossDepartment of Virology, Animal and Plant Health Agency (APHA-Weybridge), Woodham Lane, Addlestone, Surrey KT15 3NB, United Kingdom.ORCID https://orcid.org/0000-0001-7889-8218

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Newcastle disease (ND), caused by virulent strains of avian paramyxovirus type-1 (APMV-1), is one of the most important poultry diseases globally due to its economic impact and endemicity in lower- and middle-income countries. A variant of APMV-1 is endemic in Columbiformes (pigeons and doves) worldwide and is commonly termed pigeon paramyxovirus-1 (PPMV-1). Since its initial detection in the 1980s, PPMV-1 has caused numerous ND outbreaks in poultry, including in high-income countries, and was the causative agent for the last ND outbreak in the British Isles in 2006. Here, we have undertaken sequencing of PPMV-1 isolates between 1983 and 2023 and define three distinct genotypes of PPMV-1 being present in the British Isles. Analysis of the contemporary VI.2.1.1.2.2 genotype, demonstrated likely incursion from mainland Europe, whilst this genotype has subsequently spread across China, with detections also occurring in Australia. The presence of a virulent fusion-gene cleavage site in sequences highlights the continued risk to poultry from PPMV-1 genotypes, which were detected in pigeons and doves across the British Isles.

Indexed as

British Islescolumbiformesgenotype changespigeon paramyxovirus-1viral evolution

Identifiers

PMID41089326
PMCPMC12516948

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.