Evidence map›Paper›PMID 41089280›Full record

ArticleFrontiers in endocrinology2025

Association between Geriatric Nutrition Risk Index and depression in older hemodialysis patients with and without type 2 diabetes mellitus: a multicenter cross-sectional study.

Jinwen Zhang, Jing Gao, Siqin Gaowa, Peipei Han, Xiaoyu Chen, Pingping Cai, Jiangling Guo, Qianhao Wu, Jingjie Miao, Chengzhang Zhao and 4 more

Abstract readMulticenter Study
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jinwen Zhang *Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jing Gao *General Practice Clinic, Pujiang Community Health Service Center in Minhang District, Shanghai, China.
Siqin Gaowa *Department of Cardiovascular, Inner Mongolia People's Hospital, Inner Mongolia, China.
Peipei HanDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Xiaoyu ChenDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Pingping CaiSchool of Health, Fujian Medical University, Fujian, China.
Jiangling GuoShanghai University of Traditional Chinese Medicine, Shanghai, China.
Qianhao WuShanghai University of Traditional Chinese Medicine, Shanghai, China.
Jingjie MiaoShanghai University of Traditional Chinese Medicine, Shanghai, China.
Chengzhang ZhaoDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Keying ZhangDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Lingyao KongDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Jing ShuiDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Qi GuoShanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The purpose of this study was to observe the relationship between the Geriatric nutrition risk index (GNRI) and depression in the presence or absence of type 2 diabetes mellitus (T2DM) in older adults undergoing hemodialysis. Design: In this multicenter cross-sectional study, 684 clinically stable hemodialysis patients aged ≥60 years (431 men; mean age: 69.6 ± 6.6 years) were included from seven dialysis units in Shanghai, China. Results: Hemodialysis patients with diabetes had a high prevalence of depression (39.4%). In diabetes patients, GNRI was associated with depression after adjusting covariates [OR=0.984; 95% confidence interval (CI) = 0.969-0.999, Conclusions: This cross-sectional study examines the relationship between the GNRI and depression in hemodialysis patients with T2DM rather than the non-T2DM group. Further studies are needed to investigate more causal relationships between GNRI and depression in patients with T2DM.

Indexed as

DepressionDiabetes Mellitus, Type 2Geriatric AssessmentNutritional StatusNutrition AssessmentRenal DialysisAgedAged, 80 and overChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsdepressionGeriatric nutritional risk indexhemodialysismalnutritiontype 2 diabetes mellitus

Identifiers

PMID41089280
PMCPMC12515659

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.