Evidence map›Paper›PMID 41089268›Full record

ArticleFrontiers in neural circuits2025

Loss of 5-HT

Margaret I Sim, Derin Birch, Amr A Mahrous, C J Heckman, Vicki M Tysseling

Abstract read
In one paragraph

Article in Frontiers in neural circuits, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Margaret I SimDepartment of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine Northwestern University, Chicago, IL, United States.
Derin BirchDepartment of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine Northwestern University, Chicago, IL, United States.
Amr A MahrousDepartment of Neuroscience, Feinberg School of Medicine Northwestern University, Chicago, IL, United States.
C J HeckmanDepartment of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine Northwestern University, Chicago, IL, United States.
Vicki M TysselingDepartment of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine Northwestern University, Chicago, IL, United States.

Funding

Motoneuron mortality in neurodegenerative diseases induced by homeostatic dysregulation of excitabilityR01NS110953 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BINDER, MARC D, HECKMAN, CHARLES · 2019 to 2023
$2.8M
Effect of Injury Severity and Location on Spasms Post SCIK01HD084672 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI TYSSELING, VICKI M · 2015 to 2019
$653k
NICHD NIH HHS K01 HD084672NINDS NIH HHS R01 NS110953
6 · The paper itself

Abstract

The 5-HT

Indexed as

Motor ActivityReceptor, Serotonin, 5-HT2CSex CharacteristicsSpinal Cord InjuriesAnimalsFemaleLocomotionMaleMiceMice, Inbred C57BLMice, KnockoutSpinal Cord5-hydroxytryptamine2C receptor, mouseReceptor, Serotonin, 5-HT2Chyperreflexialocomotionpersistent inward currentsserotoninspinal cord injuryspinal motoneurons

Identifiers

PMID41089268
PMCPMC12515959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.