Evidence map›Paper›PMID 41089227›Full record

ReviewIJTLD open2025

Risks and consequences of TB and its prevention in cost-utility analyses among immigrants: a systematic review.

S D Robayo, C M Tansey, K Romanowski, J R Campbell

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in IJTLD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

S D RobayoDepartment of Experimental Medicine, McGill University, Montreal, Canada.
C M TanseyRespiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, Canada.
K RomanowskiDepartment of Global and Public Health, McGill University, Montreal, Canada.
J R CampbellRespiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn low-TB incidence countries, foreign-born populations bear a disproportionate share of the TB burden. Cost-utility analyses of TB preventive treatment (TPT) programs among immigrants, however, have yielded divergent conclusions. We conducted a systematic review to evaluate how studies have considered the risks and consequences of TB disease and TPT.

methodsWe searched PubMed and Embase for studies published from 1

resultsOf the 5,142 records screened, 14 studies met the inclusion criteria. Major adverse events (AEs) were the most frequently considered consequence of TPT with estimated risk ranging from 0% to 6% and mean associated annual disutility from major AEs was 0.017 QALYs, which varied substantially (coefficient of variation [CV)]: 1.2). All studies considered health disutility due to TB disease, with annual disutility ranging from 0.04 to 0.2 (mean: 0.11, CV: 0.4).

conclusionsThere is wide variation in how risks and consequences of TPT and TB disease are considered in studies evaluating TB infection treatment programs.

Indexed as

economic evaluationglobal healthinfectious diseasepublic healthTB infectiontuberculosis

Identifiers

PMID41089227
PMCPMC12517258

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.