Evidence map›Paper›PMID 41089225›Full record

ArticleIJTLD open2025

Towards TB elimination in Malawi: a 5-year analysis of key indicators for TB control using surveillance data.

H H Twabi, T C Msosa, M Mukoka, I Mwaluka, B Girma, T Sikwese, J Mpunga, T Mwenyenkulu, D Chimatiro, K Mbendera and 2 more

Abstract read
In one paragraph

Article in IJTLD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

H H TwabiKamuzu University of Health Sciences, Blantyre, Malawi.
T C MsosaKamuzu University of Health Sciences, Blantyre, Malawi.
M MukokaKamuzu University of Health Sciences, Blantyre, Malawi.
I MwalukaNational Tuberculosis and Leprosy Elimination Programme, Ministry of Health, Lilongwe, Malawi.
B GirmaNational Tuberculosis and Leprosy Elimination Programme, Ministry of Health, Lilongwe, Malawi.
T SikweseKamuzu University of Health Sciences, Blantyre, Malawi.
J MpungaNational Tuberculosis and Leprosy Elimination Programme, Ministry of Health, Lilongwe, Malawi.
T MwenyenkuluNational Tuberculosis and Leprosy Elimination Programme, Ministry of Health, Lilongwe, Malawi.
D ChimatiroNational Tuberculosis and Leprosy Elimination Programme, Ministry of Health, Lilongwe, Malawi.
K MbenderaNational Tuberculosis and Leprosy Elimination Programme, Ministry of Health, Lilongwe, Malawi.
J SimbeyeUniversity of Malawi, Zomba, Malawi.
M NliwasaKamuzu University of Health Sciences, Blantyre, Malawi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalawi's TB Control Programme emphasises data-driven approaches for monitoring TB control efforts, but programmatic indicators have never been systematically evaluated. This study evaluates the performance of Malawi's TB Control Programme, providing insights into national trends, geographical distributions, and programmatic gaps in TB care.

methodsAggregate TB data collected through Malawi's District Health Information System from 2018 to 2022 were analysed cross-sectionally. We analysed trends in TB incidence and case notification rates (CNRs), calculated performance indicators, and assessed district-level variations using time-series plots and statistical comparisons. Population estimates were derived from the 2018 census and adjusted for annual growth.

findingsMalawi reported 18,025 new persons with TB in 2022. From 2005 to 2018, TB incidence and CNRs declined by 68.6% and 54.5%, respectively. The highest CNRs were recorded among men aged 35-64 years. Treatment success rates improved overall, reaching 89.2% in 2022, though disparities persisted for HIV-positive patients and those treated at tertiary facilities.

conclusionChallenges remain in Malawi's TB control efforts, particularly in addressing case detection gaps in high-burden districts and improving outcomes for vulnerable populations. Strengthening active case finding, enhancing diagnostic capacity, and addressing socio-economic determinants of health are essential for sustaining progress and achieving END-TB Strategy goals.

Indexed as

case notificationsepidemiologyMalawitrendstuberculosis

Identifiers

PMID41089225
PMCPMC12517256

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.