Evidence map›Paper›PMID 41089114›Full record

ArticleCureus2025

Total Intravenous Anaesthesia and an Opioid-Sparing Strategy for an Extended Left Hemihepatectomy with Total Caudate Resection, Total Hepatic Vascular Exclusion, and Venovenous Bypass: An Integrative Anaesthesia Approach.

Sing Ying Pang, Jan Ngian, Selene Tan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sing Ying PangDepartment of Anaesthesiology, Singapore General Hospital, Singapore, SGP.
Jan NgianDepartment of Anaesthesiology, Singapore General Hospital, Singapore, SGP.
Selene TanDepartment of Anaesthesiology, Singapore General Hospital, Singapore, SGP.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of a 72-year-old man who underwent an open extended left hemihepatectomy and total caudate lobe resection with total hepatic vascular exclusion (THVE) for a large hepatocellular carcinoma (HCC). Anaesthetic management included the use of intrathecal opioids and total intravenous anaesthesia (TIVA) with propofol and remifentanil. Due to tumour adherence to the right hepatic vein-inferior vena cava junction, venovenous (VV) bypass and cold in situ perfusion were required. This case illustrates neurocognitive protection principles, electroencephalogram (EEG)-guided depth of anaesthesia monitoring, multimodal opioid-sparing analgesic strategies, enhanced recovery principles, and sustainable, low-emission TIVA anaesthetic maintenance, exemplifying an integrative approach in high-complexity liver surgery.

Indexed as

major hepatectomymultimodal analgesiasustainable anaesthesiatotal hepatic vascular exclusiontotal intravenous anaesthesia

Identifiers

PMID41089114
PMCPMC12516106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.