Evidence map›Paper›PMID 41089044›Full record

ArticleNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2025

Drink lemonade! Implementation of drinking 2 h before elective orthopedic surgery to reduce prolonged fasting.

Ingrid M S Heijnen, Edwin F Dierselhuis, Maartje M S Frijlink, Selma C W Musters, Getty J Huisman-de Waal, Harm H J van Noort

Abstract read
In one paragraph

Article in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Drink lemonade! Implementation of drinking 2 h before elective orthopedic surgery to reduce prolonged fasting.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ingrid M S HeijnenCentre for Trauma, Reconstructive Surgery and Movement, Radboud University Medical Centre, Nijmegen, the Netherlands.ORCID https://orcid.org/0009-0009-0404-2332
Edwin F DierselhuisDepartment of Orthopedics, Radboud University Medical Centre, Nijmegen, the Netherlands.
Maartje M S FrijlinkDepartment of Anesthesiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Selma C W MustersDepartment of Surgery, Amsterdam UMC location University of Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-8568-5496
Getty J Huisman-de WaalCentre for Trauma, Reconstructive Surgery and Movement, Radboud University Medical Centre, Nijmegen, the Netherlands.ORCID https://orcid.org/0000-0003-2811-4176
Harm H J van NoortDepartment of Surgery, Radboud University Medical Centre, Nijmegen, the Netherlands.ORCID https://orcid.org/0000-0001-9467-8434

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProlonged fasting before surgery remains common despite guidelines recommending liquid fasting for 2 h and solid fasting for 6 h preoperatively. Consuming carbohydrate-rich drinks until 2 h before surgery improves patient well-being and reduces postoperative complications and insulin resistance. Given the persistence of implementation barriers, including logistical challenges and insufficient patient education, this study aimed to implement drinking up to 2 h before elective orthopedic surgery.

methodsThe Grol and Wensing implementation approached was followed in a before-after study conducted at a Dutch academic orthopedic ward (April 2023 to May 2024), after approval by the Scientific Ethical Committee. Current practices and barriers were assessed, and tailored strategies were developed using implementation theory and taxonomies to develop implementation strategies for the identified factors, followed by integration and evaluation.

resultsImplementation included dissemination, patient-oriented, organizational, educational, and risk prevention strategies. A total of 39 patients participated in the initial analysis and 48 patients participated in the evaluation. Preoperative fasting from liquids significantly reduced from 8:20 h (IQR: 4:42-12:19 h) to 4:38 h (IQR: 2:58-6:12) by informing patients about the importance of drinking up to 2 h before surgery and to 2:45 h (IQR: 2:21-3:26) by facilitating drinking lemonade after admission when surgery would start in ≥2 h. Patients' comfort improved regarding thirst, whereas no effect was found for other symptoms. Adverse events, including postponement of surgeries and pulmonary aspirations, during surgery did not occur while accepting >1 h of fasting at the start of surgery.

conclusionsScalable implementation strategies for patient education on fasting and coordinated provision of lemonade reduced fasting duration among elective orthopedic patients.

Indexed as

DrinkingElective Surgical ProceduresFastingOrthopedic ProceduresPreoperative CareAdultAgedBeveragesFemaleHumansMaleMiddle AgedNetherlandsPatient Education as TopicPostoperative ComplicationsTime Factorscarbohydrate‐rich drinksenhanced recovery after surgeryimplementationinterprofessional collaborationpatient comfortpreoperative fastingsurgery

Identifiers

PMID41089044
PMCPMC12590338

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.