Evidence map›Paper›PMID 41089040›Full record

ArticlePediatric obesity2025

Relative Fat Mass as an Estimator of Abdominal Adiposity in Youth Across the BMI Spectrum from Normal Weight to Obesity.

Wonhee Cho, Joon Young Kim, Silva Arslanian

Abstract read
In one paragraph

Article in Pediatric obesity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wonhee ChoDepartment of Exercise Science, David B. Falk College of Sport, Syracuse University, Syracuse, New York, USA.
Joon Young KimDepartment of Exercise Science, David B. Falk College of Sport, Syracuse University, Syracuse, New York, USA.
Silva ArslanianCenter for Pediatric Research in Obesity and Metabolism and the Division of Pediatric Endocrinology, Diabetes and Metabolism, University of Pittsburgh, School of Medicine, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
CHILDHOOD METABOLIC MARKERS OF ADULT MORBIDITY IN BLACKSR01HD027503 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ARSLANIAN, SILVA A · 1997 to 2009
$2.1M
INSULIN RESISTANCE IN CHILDHOODK24HD001357 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ARSLANIAN, SILVA A · 2000 to 2011
$1.0M
National Center for Advancing Translational Sciences Clinical and Translational Science Award UL1TR000005National Institute of Child Health and Human Development K24-HD01357National Institute of Child Health and Human Development R01-HD27503NCATS NIH HHS UL1 TR000005NCRR NIH HHS UL1 RR024153NCRR NIH HHS UL1-RR024153NICHD NIH HHS K24 HD001357NICHD NIH HHS R01 HD027503
6 · The paper itself

Abstract

backgroundRelative fat mass (RFM) has been used to estimate whole-body fat percentage (%BF). However, whether RFM can mirror abdominal adiposity is unknown.

objectiveIn youth, we examined if RFM reflects abdominal adiposity, if there are age/race/sex differences in the relationships between RFM and abdominal adiposity, and if our present-youth-cohort-derived RFM (RFM-Y) improves the prediction of %BF and abdominal adiposity.

methodsIn 358 youth (aged 10-19 years; 168 black/198 white) with normal weight and overweight/obesity (without secondary or syndromic obesity), visceral (VAT), subcutaneous (SAT) and total abdominal adipose tissue (TAT) were assessed by MRI/CT and %BF with DXA. RFM was calculated for ages 10-14 years as [74 - (22 × height/waist circumference [WC]) + (5 × sex)] and 15-19 years as [64 - (20 × height/WC) + (12 × sex)]; sex = 0 for boys, 1 for girls. To develop and validate RFM-Y, linear regression, concordance correlation coefficient, Bland-Altman plots and intraclass correlation coefficient were conducted.

resultsRFM associated with VAT, SAT and TAT (r = 0.66, 0.79, 0.79, respectively; all p < 0.001). The slope was significantly greater in (a) younger versus older youth for VAT, SAT and TAT; (b) whites versus blacks for VAT; and (c) girls versus boys for SAT and TAT. RFM-Y versus traditional RFM showed improved predictive ability for %BF (R

conclusionsRFM reflects abdominal adiposity besides %BF and could be used in longitudinal/interventional youth trials, obviating the need for expensive imaging to assess changes in total and abdominal adiposity.

Indexed as

Abdominal FatAdiposityBody Mass IndexObesity, AbdominalPediatric ObesityAbsorptiometry, PhotonAdolescentBlack or African AmericanChildFemaleHumansMagnetic Resonance ImagingMaleWaist CircumferenceWhiteYoung Adultabdominal adiposityobesityrelative fat masstotal body adiposityyouth

Identifiers

PMID41089040
PMCPMC12590103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.