ArticleTransfusion2025
Patient characteristics and clinical determinants of outpatient red cell transfusions.
Article in Transfusion, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Patient characteristics and clinical determinants of outpatient red cell transfusions.Transfusion · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a knowledge gap in the outpatient transfusion practice of red blood cells (RBC) according to optimal trigger, dose, and interval as well as which patients are in need of outpatient transfusion. STUDY DESIGN AND
methodsThis single-center retrospective analysis investigates RBC transfusion practices in 804 patients with 5591 visits.
resultsBlood disorders and solid tumors were the primary indications for transfusion, accounting for 82% of RBC use. Median (interquartile range) pretransfusion hemoglobin (Hb) level was 7.5 (6.9;8.1)g/dL. Linear regression models revealed that Hb increased by 1.04 g/dL per unit transfused and identified the concomitant transfusion of platelets, male sex, higher height, weight, and lower pre-transfusion Hb level as negative factors for the increase in Hb. Factors that correlate with Hb decline after transfusion include lower reticulocytes, male sex, height, and concomitant platelet transfusion. A longer interval to next transfusion was associated with higher reticulocyte counts, higher pre-transfusion Hb levels and number of units transfused. According to our models, the potential for reducing the use of RBC through single-unit transfusions decreases with increasing height, concomitant platelet transfusions, and lower pretransfusion Hb levels and is going along with a shorter interval to next transfusion. Nonsevere adverse reactions occurred in ≤0.24% of transfusions.
conclusionThese results highlighted the effect of patient age, sex, Hb, height, and weight on outpatient RBC transfusion. These variables have to be considered in clinical practice and trials evaluating patient outcomes.
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