Evidence map›Paper›PMID 41088779›Full record

ArticleJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG2026

Cutaneous non-tuberculous mycobacterial infections: A retrospective study of 94 cases from Germany.

Luisa Bopp, Nicolai Deresz, Henning Klapproth, Isabelle Suárez, Jonathan Jantsch, Mario Fabri, Esther von Stebut

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Article in Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Luisa BoppDepartment of Dermatology and Venereology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-9089-5228
Nicolai DereszDepartment of Dermatology, University Medical Center Mainz, Mainz, Germany.
Henning KlapprothDepartment of Dermatology and Venereology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
Isabelle SuárezDepartment I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Jonathan JantschInstitute for Medical Microbiology, Immunology, and Hygiene, University Hospital Cologne and Faculty of Medicine, University of Cologne, Cologne, Germany.
Mario FabriDepartment of Dermatology and Venereology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
Esther von StebutDepartment of Dermatology and Venereology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0001-9802-9642

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCutaneous non-tuberculous mycobacterial infections (NTM) remain a diagnostic and therapeutic challenge. The aim of this study was to characterize cutaneous NTM infections in Germany over a 24-year-period. PATIENTS AND

methods73 patients with cutaneous NTM infections diagnosed at 17 different German University Hospitals from 2000-2011 and 21 patients treated at the Department of Dermatology of the University Hospital Cologne, from 2010-2024. Retrospective analysis of patient, demographic, clinical information, and data on different diagnostic workups and therapeutic approaches/responses.

resultsTogether, 94 cases were analyzed (71% males, mean age 50, > 75% immunocompetent). Exposure to fish tanks was the dominant risk factor. Pathogen detection by nucleic acid amplification test and/or culture was successful in 76%. The most common pathogen was Mycobacterium (M.) marinum (> 65%), followed by M. abscessus/chelonae. Immunosuppression was associated with NTM other than M. marinum. Over 90% were treated with oral antibiotics, in more than 50% with a single antibiotic (mostly clarithromycin). The most common combination was clarithromycin plus rifampicin. The mean duration of therapy was more than 4 months. Complications, adverse events, and relapses were rare.

conclusionsOur findings highlight that there is a need for standardized diagnostic procedures- and therapeutic recommendations for cutaneous NTM infections.

Indexed as

Mycobacterium Infections, NontuberculousSkin Diseases, BacterialAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsClarithromycinFemaleGermanyHumansMaleMiddle AgedRetrospective StudiesRifampinRisk FactorsAnti-Bacterial AgentsClarithromycinRifampinfish tank granulomamycobacteriaeMycobacterium marinumNTM

Identifiers

PMID41088779
PMCPMC13140123

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.