Evidence map›Paper›PMID 41088414›Full record

ArticleParasites & vectors2025

Do not let your guard down! Prevalence of Dirofilaria immitis and Dirofilaria repens in dogs entering shelters in northern Italy.

Marco Genchi, Luigi Venco, Ornella Melideo, Laura Kramer, Marta Fozzer, Alice Vismarra

Abstract read
In one paragraph

Article in Parasites & vectors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Geographical Distribution and Molecular Characterization ofAnimals : an open access journal from MDPI · 2026
    Article
  2. International journal for parasitology. Parasites and wildlife · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marco GenchiDepartment of Veterinary Sciences, University of Parma, Strada del Taglio, 10, 43126, Parma, Italy.
Luigi VencoOspedale Veterinario Città di Pavia, Viale Cremona, 179, 27100, Pavia, Italy.
Ornella MelideoElanco Italia, Via Ludovico di Breme, 13, 20156, Milano, Italy.
Laura KramerDepartment of Veterinary Sciences, University of Parma, Strada del Taglio, 10, 43126, Parma, Italy.
Marta FozzerDepartment of Veterinary Sciences, University of Parma, Strada del Taglio, 10, 43126, Parma, Italy.
Alice VismarraDepartment of Veterinary Sciences, University of Parma, Strada del Taglio, 10, 43126, Parma, Italy. alice.vismarra@unipr.it.

Funding

EU funding within the NextGenerationEU MUR PNRR Extended Partnership initiative on Emerging Infectious Diseases, INF ACT Cascade Open Call 2023 COC 1 2023 UNIPD Project no. PE00000007, INF ACT
6 · The paper itself

Abstract

backgroundIn Italy, the area of highest prevalence for canine heartworm disease (CHWD) has historically been along the Po River Valley in the northern area of the country, where prevalence in the mid-nineties ranged from 31% to 98%. Currently, increased awareness among practitioners and the availability of preventives have led to a dramatic decrease in prevalence in the area, although cases of CHWD continue to be diagnosed, suggesting the presence of canine reservoirs, including unowned dogs.

methodsThe aim of the present study was to determine the prevalence of Dirofilaria spp. in stray dogs entering shelters located in the Po River Valley of northern Italy by using the modified Knott's test and by antigenic testing.

resultsOut of the 510 dogs tested, 173 (33.9%) were positive for circulating microfilariae: 15.7% (80/510) with D. immitis, 6.9% (35/510) with D. repens, and 11.4% (58/510) with a mixed infection.

conclusionsUnowned dog populations represent an important reservoir for the parasite, allowing D. immitis to remain in a given geographical area and increasing the risk of exposure to all dogs.

Indexed as

Dirofilaria immitisDirofilaria repensDirofilariasisDog DiseasesAnimalsAntigens, HelminthDisease ReservoirsDogsFemaleItalyMalePrevalenceAntigens, HelminthDirofilaria immitisDirofilaria repensDogsNorthern ItalyPo River ValleyPrevalence

Identifiers

PMID41088414
PMCPMC12522961

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.