Evidence map›Paper›PMID 41088365›Full record

ArticleScandinavian journal of trauma, resuscitation and emergency medicine2025

Associations between four standard interventions as well as epinephrine use and sustained ROSC, 30-Day and one-year survival of patients in traumatic cardiac arrest: a multicentre, retrospective cohort study.

Romana Erblich, Jens Meier, Tina Tomic Mahecic, Matthias Noitz, Stephan Kalb, Helmut Trimmel, Julian M Baumkirchner, Maximilian Havlicek, Wolfgang Voelckel, Luca Carenzo and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Scandinavian journal of trauma, resuscitation and emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Romana ErblichDepartment of Anesthesiology and Critical Care Medicine, Kepler University Hospital and Johannes Kepler University, Krankenhausstrasse 9, Linz, 4020, Austria.
Jens MeierDepartment of Anesthesiology and Critical Care Medicine, Kepler University Hospital and Johannes Kepler University, Krankenhausstrasse 9, Linz, 4020, Austria.
Tina Tomic MahecicDepartment of Anesthesiology and Intensive Care Medicine, Clinical Hospital Centre Zagreb, Zagreb, Croatia.
Matthias NoitzDepartment of Anesthesiology and Critical Care Medicine, Kepler University Hospital and Johannes Kepler University, Krankenhausstrasse 9, Linz, 4020, Austria.
Stephan KalbDepartment of Anesthesiology and Critical Care Medicine, Kepler University Hospital and Johannes Kepler University, Krankenhausstrasse 9, Linz, 4020, Austria.
Helmut TrimmelChristophorus Air Rescue, OEAMTC, Vienna, Austria.
Julian M BaumkirchnerDepartment of Urology, University Hospital Zürich, Zürich, Switzerland.
Maximilian HavlicekDepartment of Anesthesiology and Critical Care Medicine, Kepler University Hospital and Johannes Kepler University, Krankenhausstrasse 9, Linz, 4020, Austria.
Wolfgang VoelckelChristophorus Air Rescue, OEAMTC, Vienna, Austria.
Luca CarenzoDepartment of Anaesthesia and Intensive Care Medicine, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy.
Martin W DünserDepartment of Anesthesiology and Critical Care Medicine, Kepler University Hospital and Johannes Kepler University, Krankenhausstrasse 9, Linz, 4020, Austria. martin.duenser@i-med.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe evidence to support guideline-recommended interventions in traumatic cardiac arrest (TCA) is low.

methodsThis multicentre, retrospective study included 996 paediatric and adult patients with out-of-hospital TCA (01/2010-12/2019). Demographic, clinical, and pre-hospital data, binary delivery of five core interventions, and outcomes were collected. Crude (crosstabs) and adjusted (logistic regressions) odds ratios (OR) with 95% confidence intervals (95%CI) were calculated to determine the associations between single interventions and outcomes.

resultsA sustained return-of-spontaneous-circulation (ROSC) was achieved in 341 subjects (34.2%). The 30-day and 1-year survival rates were 7.4 and 6.6%, respectively. The 95%CIs of the crude ORs for sustained ROSC were greater than one for all interventions. The 95%CIs of the crude ORs for 30-day and 1-year survival were greater than one for fluid infusion (20.5, 5.0-84.4), pelvic binder application (11.2, 3.3-37.7), as well as airway protection and ventilation with 100% oxygen (3.7, 1.5-9.5), but not for epinephrine use (1.4, 0.8-2.5) or bilateral chest decompression (1.0, 0.5-2.0). The 95%CIs of the adjusted ORs of fluid infusion (7.8, 4.7-13.5), application of a pelvic binder (8.9, 1.3-17.6), airway protection and ventilation with 100% oxygen (4.5, 2.5-8.7), as well as epinephrine use (4.0, 2.6-6.2) were greater than one for sustained ROSC. For 30-day and 1-year survival, the 95%CIs of the adjusted odds ratios of fluid infusion (30-day: 19.9, 4.1-359; 1-year: 16.8, 3.4-305) and pelvic binder application (30-day: 14.4, 2.3-90.8; 1-year: 19.8, 3.1-127), but not airway protection and ventilation with 100% oxygen (30-day: 1.9, 0.7-6.6; 1-year: 1.4, 0.5-5.1), epinephrine use (30-day: 1.0, 0.5-2.1; 1-year: 0.7, 0.3-1.5) or bilateral chest decompression (30-day: 1.1, 0.4-2.8; 1-year: 1.5, 0.6-3.9) were greater than one. The number of interventions correlated with the rates of sustained ROSC (Φ = 0.405; p < 0.001), 30-day (Φ = 0.168; p < 0.001), and 1-year (Φ = 0.169; p < 0.001) survival.

conclusionsOur results suggest that fluid infusion, application of a pelvic binder, as well as airway protection and ventilation with 100% oxygen in TCA are associated with higher rates of sustained ROSC, 30-day and 1-year survival. A bundled approach of these interventions might be beneficial. The high 30-day and 1-year survival rates underscore the value and effectiveness of resuscitation efforts in TCA patients.

Indexed as

Cardiopulmonary ResuscitationEpinephrineOut-of-Hospital Cardiac ArrestWounds and InjuriesAdultAgedChildFemaleHumansMaleMiddle AgedRetrospective StudiesReturn of Spontaneous CirculationSurvival RateVasoconstrictor AgentsEpinephrineVasoconstrictor AgentsHelicopter emergency medical serviceInterventionsReturn of spontaneous circulationSurvivalTraumatic cardiac arrest

Identifiers

PMID41088365
PMCPMC12522251

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.