Evidence map›Paper›PMID 41088287›Full record

ReviewGlobalization and health2025

Pharmaceutical access in Brazil: challenges and opportunities.

Cristina M Ruas, Ronaldo Portela, Francisco de Assis Acurcio, Juliana Alvares-Teodoro, Augusto Afonso Guerra Júnior, Aaron S Kesselheim

Abstract readReview
In one paragraph

Review in Globalization and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristina M RuasSocial Pharmacy Department, Faculty of Pharmacy, Federal University of Minas Gerais, Presidente Antonio Carlos Avenue, 6627, Belo Horizonte, Minas Gerais, CEP: 31270-901, Brazil. crisruas@ufmg.br.
Ronaldo PortelaSocial Pharmacy Department, Faculty of Pharmacy, Federal University of Minas Gerais, Presidente Antonio Carlos Avenue, 6627, Belo Horizonte, Minas Gerais, CEP: 31270-901, Brazil.
Francisco de Assis AcurcioSocial Pharmacy Department, Faculty of Pharmacy, Federal University of Minas Gerais, Presidente Antonio Carlos Avenue, 6627, Belo Horizonte, Minas Gerais, CEP: 31270-901, Brazil.
Juliana Alvares-TeodoroSocial Pharmacy Department, Faculty of Pharmacy, Federal University of Minas Gerais, Presidente Antonio Carlos Avenue, 6627, Belo Horizonte, Minas Gerais, CEP: 31270-901, Brazil.
Augusto Afonso Guerra JúniorSocial Pharmacy Department, Faculty of Pharmacy, Federal University of Minas Gerais, Presidente Antonio Carlos Avenue, 6627, Belo Horizonte, Minas Gerais, CEP: 31270-901, Brazil.
Aaron S KesselheimBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001
6 · The paper itself

Abstract

backgroundBrazil faces challenges in ensuring equitable access to prescription drugs for its population. Socioeconomic disparities contribute to health inequalities, impacting access to health care services, including medicines. Brazil's Unified Health System aims to provide universal health care coverage, but only 30·5% of people obtain all of their prescribed medications through public channels free of charge. The objective is to characterize the Brazilian pharmaceutical market to better understand the underlying factors affecting medicine accessibility.

methodsWe conducted a literature review to assess the current state of the pharmaceutical market and prescription drug access in Brazil.

findingsThe Brazilian pharmaceutical market is extensive but highly concentrated, characterized by low investment in original research and development (R&D) and a heavy reliance on imported active pharmaceutical ingredients. Challenges include vulnerability to economic and external factors. Additionally, high medicine prices, prioritization of production of expensive new medicines over those for prevalent diseases, and shortages contribute to inequalities in access. Regulatory issues, underfunding of health care, and legal discrepancies exacerbate these challenges but also present opportunities for reform.

interpretationThe policymakers should prioritize enhancing R&D investment, reducing dependency on international markets, strengthening regulatory frameworks, and improving health care system efficiency to ensure reliable access to essential medicines.

Indexed as

Health Services AccessibilityPrescription DrugsBrazilDrugs, EssentialHealthcare DisparitiesHumansDrugs, EssentialPrescription DrugsDrug costsHealth care financingHealth inequalitiesHealth systemsPharmaceutical industry

Identifiers

PMID41088287
PMCPMC12522811

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.