ArticleBMC surgery2025
Safety and efficacy analysis of different embolization methods of Glubran-2 glue in the treatment of arterial gastrointestinal bleeding.
Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study summarized our experience in treating arterial gastrointestinal bleeding with Glubran-2 glue embolization, and analyzed efficacy and safety of Punctate embolism and Flake Embolism.
methodClinical data collected between January 2009 and January 2021 from patients with arterial gastrointestinal bleeding treated with Glubran-2 glue were analyzed retrospectively. Subsequently, univariate analysis and binary logistic regression analysis were performed to examine the risk factors associated with clinical outcomes and 30-day postoperative mortality. Finally, according to the embolization methods, it is divided into Punctate embolism(n=37) and Flake embolism(n༝44), and the curative effects of the two groups of embolization methods are analyzed.
resultFor a total of 81 patients, the technical success rate was 100%, the clinical success rate was 71.6% (n = 58), and the 30-day mortality rate post-endovascular interventions was 13.6% (n = 11). In addition, there was a significant negative correlation between the volume of blood transfusion and clinical outcome (P < 0.05), Furthermore, clinical outcome, coagulopathy, and heart rate were identified as independent risk factors for the 30-day mortality rate post-endovascular interventions. Finally, the clinical success rate (86.5%VS59.1%) of Punctate embolism is much higher than that of Flake embolism, and the mortality rate (5.4%VS20.5%) is obviously lower (P < 0.05).
conclusionThe findings of the study confirm that the use of Glubran-2 glue embolization offers a secure and effective treatment strategy for treating arterial gastrointestinal bleeding. The results suggest that punctate embolism may be associated with improved outcomes compared to flake embolism.
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