Evidence map›Paper›PMID 41088050›Full record

Trial reportBMC musculoskeletal disorders2025

Application of saphenous nerve infrapatellar branch protection technique in total knee arthroplasty.

Zhi-Qiang Mao, Kai Li, Zhou Zhang, Ting Li, Jian-Hua Lu, Meng-Qiang Fan, Xiao-Bing Chu

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhi-Qiang Mao *Department of Orthopaedics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Kai Li *Department of Orthopaedics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Zhou Zhang *Changxing County Hospital of Traditional Chinese Medicine, Huzhou, China.
Ting Li *Center for Plastic and Reconstructive Surgery, Department of Plastic and Reconstructive Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Jian-Hua LuDepartment of Orthopaedics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China. lujianhua@163.com.
Meng-Qiang FanDepartment of Orthopaedics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China. 741216599@qq.com.
Xiao-Bing ChuDepartment of Orthopaedics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China. 18507037510@163.com.

Funding

Natural Science Foundation of China;Zhejiang Province Leading Geese Plan;Science and Technology Program of Traditional Chinese Medicine in Zhejiang Province; Grant number 82305040;2025ZR028;2024C03148;
6 · The paper itself

Abstract

objectiveThis randomized controlled trial conducted a comparative analysis of postoperative outcomes between a modified anteromedial incision with saphenous nerve protection and the traditional medial parapatellar approach in total knee arthroplasty (TKA). We aimed to test the hypothesis that the nerve-sparing modified technique would significantly reduce postoperative anterior knee numbness and pain while maintaining surgical feasibility.

methodsSixty-eight TKA candidates (January 2022-June 2023) were prospectively randomized into two groups: Modified (n = 34) and Traditional (n = 34) approaches. The modified technique featured an anteromedial incision with infrapatellar branch visualization and preservation, whereas the control group received the traditional medial parapatellar exposure. Primary outcomes included numbness area and the Visual Analog Scale score; secondary outcomes encompassed surgical parameters (duration, blood loss) and functional recovery (Hospital for Special Surgery Knee score).

resultsThirty one patients were randomized to the M group and 29 patients allocated to the T group. Compared to the T group, the M group demonstrated significantly lower VAS scores at 3 days, 7 days, and 2 weeks postoperatively, with statistical significance (P < 0.05). The M group showed a statistically significant reduction in the area of numbness compared to the T group at all postoperative follow-up intervals: 2 weeks, 1 month, 3 months, 6 months, and 1 year (P < 0.05 for all time points). However, postoperative HSS scores did not differ significantly between the M group and the T group at any follow-up interval (P > 0.05).

conclusionThe nerve-preserving modified approach achieved superior patient-reported outcomes (PROs) in reducing anterior knee numbness and early postoperative pain without compromising prosthesis implantation accuracy or functional recovery trajectories, suggesting its potential as a standardized refinement in TKA surgical protocols.

trial registrationChinese Clinical Trial Registry, ChiCTR2500107220, 6 August 2025, retrospectively registered.

Indexed as

Arthroplasty, Replacement, KneeHypesthesiaPostoperative PainAgedFemaleHumansKnee JointMaleMiddle AgedPain MeasurementPatellaProspective StudiesRecovery of FunctionTreatment OutcomeKnee jointModified surgeryProtection technologySaphenous nerveTotal knee arthroplasty

Identifiers

PMID41088050
PMCPMC12523096

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.