Evidence map›Paper›PMID 41087990›Full record

ReviewBMC neurology2025

Myasthenia gravis complicated by intestinal pseudo-obstruction: a case report and literature review.

Yangtao Lin, Chaoyue Zhang, Zhishan Zhong, Yufei Deng, Haocheng Luo, Xiaojun Yang, Qilong Jiang

Abstract readCase ReportsReview
In one paragraph

Review in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yangtao LinGuangzhou University of Chinese Medicine, Dayuan at No. 14 Airport Road, Guangdong, 510405, Guangzhou, China.
Chaoyue ZhangGuangzhou University of Chinese Medicine, Dayuan at No. 14 Airport Road, Guangdong, 510405, Guangzhou, China.
Zhishan ZhongGuangzhou University of Chinese Medicine, Dayuan at No. 14 Airport Road, Guangdong, 510405, Guangzhou, China.
Yufei DengGuangzhou University of Chinese Medicine, Dayuan at No. 14 Airport Road, Guangdong, 510405, Guangzhou, China.
Haocheng LuoGuangzhou University of Chinese Medicine, Dayuan at No. 14 Airport Road, Guangdong, 510405, Guangzhou, China.
Xiaojun YangFirst Affiliated Hospital of Guangzhou University of Chinese Medicine, Dayuan at No. 16 Airport Road, Guangdong, 510405, Guangzhou, China. yly901@126.com.
Qilong JiangFirst Affiliated Hospital of Guangzhou University of Chinese Medicine, Dayuan at No. 16 Airport Road, Guangdong, 510405, Guangzhou, China. jiangqilong5119@gzucm.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMyasthenia gravis (MG) is an autoimmune disease characterized by fluctuating weakness of skeletal muscles, usually without involvement of gastrointestinal muscle groups. However, when accompanied by intestinal pseudo-obstruction (IPO), patients may present with gastrointestinal symptoms, complicating prompt diagnosis. We report two new cases of MG complicated by IPO, detailing their clinical course and management.

methodsA case report and review of the literature.

resultsWe report two new cases of young male MG complicated by IPO. Both patients were admitted with symptoms indicative of intestinal obstruction and achieved clinical remission following thymectomy. We identified a total of 14 cases of MG complicated by IPO, including 12 previously reported in the literature. Of these cases, IPO was the initial clinical manifestation in 64.3% (9/14). 12 (85.7%) of them were correlated with thymoma, and only one patient did not undergo thymectomy. Ten patients showed clinical improvement, while the remaining four succumbed to the disease progression or complications.

conclusionsIt is challenging to diagnose MG complicated by IPO at the initial presentation. We should be careful to avoid unnecessary colectomies in the treatment process.

Indexed as

Intestinal Pseudo-ObstructionMyasthenia GravisAdultHumansMaleThymectomyIntestinal pseudo-obstructionMyasthenia gravisThymectomy

Identifiers

PMID41087990
PMCPMC12522836

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.