Evidence map›Paper›PMID 41087951›Full record

ArticleBMC medical imaging2025

Presence of crescents in IgA nephropathy-prediction from ultrasound images using deep learning.

Xiaomin Hu, Weihan Xiao, Di Wang, Jiao Yao, Xiaoling Liu, Huaming Xian, Xisheng Xie, Chaoxue Zhang, Xiachuan Qin

Abstract read
In one paragraph

Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaomin Hu *Department of Ultrasound, West China School of Medicine, Sichuan University, Sichuan University affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, Chengdu, 610000, China.
Weihan Xiao *Department of Ultrasound, West China School of Medicine, Sichuan University, Sichuan University affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, Chengdu, 610000, China.
Di Wang *Department of Ultrasound, West China School of Medicine, Sichuan University, Sichuan University affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, Chengdu, 610000, China.
Jiao Yao *Department of Ultrasound, West China School of Medicine, Sichuan University, Sichuan University affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, Chengdu, 610000, China.
Xiaoling LiuDepartment of Ultrasound, The Second Clinical Medical College of North Sichuan Medical College, Nanchong Central Hospital, Nanchong, 637000, China.
Huaming XianDepartment of Nephrology, The Second Clinical Medical College of North Sichuan Medical College, Nanchong Central Hospital, Nanchong, 637000, China.
Xisheng XieDepartment of Nephrology, The Second Clinical Medical College of North Sichuan Medical College, Nanchong Central Hospital, Nanchong, 637000, China.
Chaoxue ZhangDepartment of Ultrasound, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China. zcxay@163.com.
Xiachuan QinDepartment of Ultrasound, West China School of Medicine, Sichuan University, Sichuan University affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, Chengdu, 610000, China. 11326636@qq.com.

Funding

the Nanchong School Science and technology strategic cooperation project 19SXHZ0165the Science and Technology Plan Project of Nanchong City 22JCYJPT0004
6 · The paper itself

Abstract

backgroundThis study aimed to develop an ultrasound (US)-based deep learning (DL) model to evaluate the presence of crescents in patients with immunoglobulin A nephropathy (IgAN).

methodsWe created a training set consisting of 2,682 US images obtained from 931 patients with IgAN at the First Affiliated Hospital of Anhui Medical University. The external testing set included 198 patients from Nanchong Central Hospital based on the same criteria. Five DL models were trained in the training set and tested in the testing set. The performance of each model was evaluated for the area under the receiver operating characteristic curve (AUC), accuracy, sensitivity, specificity, positive predictive value and negative predictive value.

resultsThe DenseNet121 model achieved an accuracy of 0.773 in the external testing set for predicting the presence of crescents, with a sensitivity of 57.6% and specificity of 87.9%.

conclusionUsing renal ultrasound imaging data, DL may be able to predict crescent status in IgAN, providing clinicians with a potentially non-invasive means to better understand crescent status in patients with IgAN. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Deep LearningGlomerulonephritis, IGAAdultFemaleHumansImage Interpretation, Computer-AssistedMaleMiddle AgedPredictive Value of TestsSensitivity and SpecificityUltrasonographyCrescentsDeep learningIgA nephropathyUltrasound

Identifiers

PMID41087951
PMCPMC12522557

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.