Genotype characteristics of two non traveler sources burkholderia pseudomallei strains isolated from clinical patients for the first time in Chongqing, China.

Gang Duan, Chunyan Liao, Gaomin Liu, Linghan Kong, Ling Wang

Abstract read

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Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Gang Duan *Chongqing Center for Disease Control and Prevention, Microbial Testing Institute, Chongqing, 400707, China.

Chunyan Liao *Chongqing Center for Disease Control and Prevention, Microbial Testing Institute, Chongqing, 400707, China.

Gaomin Liu *Chongqing Center for Disease Control and Prevention, Microbial Testing Institute, Chongqing, 400707, China.

Linghan Kong *Chongqing wanzhou District Center for Disease Control and Prevention, Chongqing, 404100, China.

Ling WangChongqing Center for Disease Control and Prevention, Microbial Testing Institute, Chongqing, 400707, China. 787704919@qq.com.

Funding

The rigorous work was made possible by generous support from the Natural Science Foundation of Chongqing CSTB2024NSCQ- MSX0795

6 · The paper itself

Abstract

In 2024, two cases of melioidosis were discovered in Chongqing, China. This was the first instance of non-traveler infection cases being found in this region. The strain characteristics and phylogenetic relationships of the two B. pseudomallei (CQ2024Bp-001 and CQ2024Bp-002) remained poorly understood. An antibiotic sensitivity test, genomic sequencing, prediction of virulence genes and ARGs, wgSNP, and MLST were performed for the two strains. The results indicated that the two strains had significant genetic differences (17197 SNPs), and CQ2024Bp-002 was a novel sequence type (ST2149). CQ2024Bp-001 carried bla

Indexed as

Burkholderia pseudomalleiGenotypeMelioidosisAnti-Bacterial AgentsChinaFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedMultilocus Sequence TypingPhylogenyPolymorphism, Single NucleotideVirulence FactorsWhole Genome SequencingAnti-Bacterial AgentsVirulence Factors

Identifiers

PMID41087946

DOI10.1186/s12879-025-11819-0

PMCPMC12522445

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