Evidence map›Paper›PMID 41087910›Full record

ArticleBMC anesthesiology2025

Surgical pleth index to predict the success of caudal block in pediatric patients under general anesthesia.

Ruchita Harchandani, Deepali Shetty, Anitha Nileshwar, Handattu Mahabaleswara Krishna, Suvajit Podder

Abstract readClinical Study
In one paragraph

Article in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Ruchita HarchandaniDepartment of Anesthesiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka State, 576104, India.ORCID http://orcid.org/0009-0001-6873-9288
Deepali ShettyDepartment of Anesthesiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka State, 576104, India.ORCID http://orcid.org/0000-0002-3354-0172
Anitha NileshwarDepartment of Anesthesiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka State, 576104, India. anitha.rshenoy@manipal.edu.ORCID http://orcid.org/0000-0002-4556-1851
Handattu Mahabaleswara KrishnaDepartment of Anesthesiology, All India Institute of Medical Sciences, Mangalagiri, 522503, Andhra Pradesh, India.ORCID http://orcid.org/0000-0002-6106-4556
Suvajit PodderDepartment of Anesthesiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka State, 576104, India.ORCID http://orcid.org/0000-0002-6852-5781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCaudal block is usually performed after general anesthesia in children, which makes it hard to assess the success of the block. The aim of this study was to determine whether the surgical pleth index can serve as an objective tool for assessing nociception and the success of caudal block in anesthetized children. METHODOLOGY: Sixty-two children aged 1-6 years, with American Society of Anesthesiologists Physical Status I and II, undergoing elective infraumbilical surgery, were included. All patients received general anesthesia with i-gel and caudal analgesia. The surgical pleth index, heart rate, and mean blood pressure were recorded throughout the procedure. Caudal block was assessed postoperatively with a gentle pinch.

resultsThe patients were divided into Group S (caudal success) and Group F (caudal failure). In both groups, the SPI decreased after induction to nearly < 50. It continued to gradually decrease to ≈30 in Group S, whereas it increased sharply with incision in Group F to ≈76. After additional analgesia with fentanyl, the surgical pleth index decreased in Group F, but the mean surgical pleth index was significantly greater than in Group S (p < 0.01). The intergroup difference in surgical pleth index persisted throughout the procedure. A receiver operating curve showed that a surgical pleth index of 43.5 before incision has a sensitivity of 83.3% and a specificity of 67.9% for predicting successful caudal block. Heart rate and blood pressure increased significantly with incision in Group F, unlike in Group S. The intergroup difference in hemodynamics disappeared after additional analgesia.

conclusionA surgical pleth index of ≤ 43.5 (which may be rounded to 40) can serve as a nociceptive index to predict the success of a caudal block in children. IEC REGISTRATION NUMBER: IEC2 549/2023 dated 19th March 2024. CLINICAL TRIALS REGISTRATION: (CTRI/2024/12/078281) dated 18th December 2024.

Indexed as

Anesthesia, CaudalAnesthesia, GeneralBlood PressureChildChild, PreschoolFemaleFentanylHeart RateHumansInfantMaleNociceptionFentanylAnalgesiaCaudalChildrenNociceptionSurgical pleth index

Identifiers

PMID41087910
PMCPMC12523174

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.