SynthesisThe journal of headache and pain2025
EEG patterns in each phase of hemiplegic migraine: a systematic review and pooled prevalence meta-analysis.
Synthesis in The journal of headache and pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHemiplegic migraine (HM) is a rare subtype of migraine with aura, and its pathophysiology is similar to that of migraine with aura, primarily involving cortical spreading depression. Electroencephalography (EEG) may serve as a valuable tool for investigating brain function in patients with hemiplegic migraine. Therefore, this study aims to synthesize available evidence through a systematic review and pooled prevalence meta-analysis to assess the types of EEG abnormalities observed in each migraine phase in patients with hemiplegic migraine and to estimate the prevalence of EEG abnormalities during the interictal period.
methodWe searched PubMed, Scopus, and Cochrane up to January 2025 and included articles, including case reports, case series, and retrospective studies that reported EEG abnormalities in hemiplegic migraine. The prevalence of abnormal EEG during the interictal phase was analyzed through pooled data analysis.
resultA total of 40 articles involving 65 patients were included in the analysis. The most common EEG abnormality During the aura phase was low-amplitude activity affecting the hemisphere contralateral to the hemiparesis, observed in 71.4% (5/7) of cases. Similarly, During the headache and post-headache phases, the most frequently observed EEG abnormality was medium- to high-amplitude slowing, particularly in the hemisphere contralateral to the hemiparesis, occurring in 54.9% (28/51) and 37.5% (9/24) of cases, respectively. Meanwhile, 78.8% (26/33) of patients' EEG recordings during the interictal phase were normal.
conclusionThis study found that the most common EEG abnormality during the aura phase was low-amplitude activity in the hemisphere contralateral to the hemiparesis, while during the headache and post-headache phases, medium- to high-amplitude focal slowing was frequently observed in the same hemisphere. EEGs during the interictal phase were mostly normal. These findings provide an overview of characteristic EEG patterns in each phase of hemiplegic migraine and may support the hypothesis that widespread cortical spreading depression precedes subcortical propagation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.