Evidence map›Paper›PMID 41087831›Full record

ArticleEarly intervention in psychiatry2025

Using a Learning Health System to Integrate Peer Support in Early Intervention Services for Psychosis in Quebec: Protocol for a Participatory, Mixed-Methods Study (the PAIRPEP Project).

Beatrice Todesco, Srividya N Iyer, Manuela Ferrari, Marc-André Roy, Marie-Hélène Morin, Julie Marguerite Deschênes, Camille Arbaud, Gabriel Julien, Annie Bossé, Mary Anne Levasseur and 1 more

Abstract read
In one paragraph

Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Beatrice TodescoNeurosciences Axis, Research Center of the Centre Hospitalier de l'Université de Montréal (CRCHUM), Quebec, Canada.
Srividya N IyerDepartment of Psychiatry, McGill University, Quebec, Canada.ORCID https://orcid.org/0000-0001-5367-9086
Manuela FerrariDepartment of Psychiatry, McGill University, Quebec, Canada.ORCID https://orcid.org/0000-0002-7530-6210
Marc-André RoyDepartment of Psychiatry and Neurosciences, Faculty of Medicine, Université Laval, Quebec, Canada.ORCID https://orcid.org/0000-0002-0123-6651
Marie-Hélène MorinDepartment of Psychosociology and Social Work, Université du Québec à Rimouski (UQAR), Rimouski, Québec, Canada.ORCID https://orcid.org/0000-0002-0549-1641
Julie Marguerite DeschênesNeurosciences Axis, Research Center of the Centre Hospitalier de l'Université de Montréal (CRCHUM), Quebec, Canada.
Camille ArbaudNeurosciences Axis, Research Center of the Centre Hospitalier de l'Université de Montréal (CRCHUM), Quebec, Canada.
Gabriel JulienNeurosciences Axis, Research Center of the Centre Hospitalier de l'Université de Montréal (CRCHUM), Quebec, Canada.
Annie BosséNeurosciences Axis, Research Center of the Centre Hospitalier de l'Université de Montréal (CRCHUM), Quebec, Canada.
Mary Anne LevasseurNeurosciences Axis, Research Center of the Centre Hospitalier de l'Université de Montréal (CRCHUM), Quebec, Canada.
Amal Abdel-BakiNeurosciences Axis, Research Center of the Centre Hospitalier de l'Université de Montréal (CRCHUM), Quebec, Canada.ORCID https://orcid.org/0000-0003-3333-9652

Funding

Echo FoundationGraham Boeckh FoundationHewitt FoundationRéseau des diplômés et donateurs de l'Université de MontréalRossy Family Foundation
6 · The paper itself

Abstract

introductionSince 2019, SARPEP (Système Apprenant Rapide pour les programmes de Premiers Épisodes Psychotiques), a rapid learning health system (RLHS) for Quebec's Early Intervention for Psychosis Services, operates to bridge the evidence-practice gap across the province. Despite strong stakeholder support and government recommendations, peer support services remained poorly available. To address this gap, since 2023, the PAIRPEP project was co-developed to support and evaluate the implementation of peer support and family peer support. This paper describes the co-designed study protocol, embedded within this RLHS.

methodsThis participatory, mixed-methods study aims to examine the implementation of the PAIRPEP intervention longitudinally over 3 years across 12 Early Intervention Services and its impact on multiple stakeholders. Informed by the Medical Research Council framework for complex interventions, the project includes a co-designed (with multiple stakeholders) multimodal capacity-building program with specific components developed to overcome barriers to integrating peer support and family peer support. Quantitative questionnaires are collected every 4 months from clinicians while youth and families can complete surveys at any convenient time, via QR codes available in clinics, through the RLHS electronic platform. Focus groups are conducted annually over 3 years with eight stakeholder groups. The analysis integrates findings using thematic synthesis and joint displays to assess convergence and divergence across methods and perspectives. RESULTS AND

conclusionThis protocol paper outlines the study's co-design, procedures and anticipated contributions. Embedding large-scale innovative intervention implementation (such as peer support) within an RLHS can foster real-time feedback, iterative refinement and inform clinical practice and policies.

Indexed as

Early Medical InterventionPeer GroupPsychotic DisordersSocial SupportAdolescentHumansMental Health ServicesQuebecearly intervention services for psychosisimplementationlearning health systemmixed methodspeer supportyouth mental health services

Identifiers

PMID41087831
PMCPMC12521639

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.