Evidence map›Paper›PMID 41087787›Full record

ArticleMedical & biological engineering & computing2026

Automated measurement of optic nerve sheath diameter using ocular ultrasound video.

Renxing Li, Weiyi Tang, Peiqi Li, Qiming Huang, Jiayuan She, Shengkai Li, Haoran Xu, Yeyun Wan, Jing Liu, Hailong Fu and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Medical & biological engineering & computing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Renxing LiShanghai Key Laboratory of Multidimensional Information Processing, East China Normal University, Shanghai, 200241, China.
Weiyi TangIntensive Care Unit, Minhang Hospital, Fudan University, Shanghai, 201199, China.
Peiqi LiSchool of Mathematics and Physics, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu, 215123, China.
Qiming HuangSchool of Artificial Intelligence and Advanced Computing, Xi'an Jiaotong-Liverpool University (Taicang Campus), Taicang, Jiangsu, 215400, China.
Jiayuan SheShanghai Key Laboratory of Multidimensional Information Processing, East China Normal University, Shanghai, 200241, China.
Shengkai LiSchool of Mathematics and Physics, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu, 215123, China.
Haoran XuKhoury College of Computer Science, Northeastern University, Boston, MA, 02115, USA.
Yeyun WanSchool of Advanced Technology, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu, 215123, China.
Jing LiuDepartment of Neonatology and NICU, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China.
Hailong FuDepartment of Anesthesiology, Changzheng Hospital, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China. fuhailong1979@163.com.
Xiang LiIntensive Care Unit, Minhang Hospital, Fudan University, Shanghai, 201199, China. 18918169826@163.com.
Jiangang ChenShanghai Key Laboratory of Multidimensional Information Processing, East China Normal University, Shanghai, 200241, China. jgchen@cee.ecnu.edu.cn.ORCID http://orcid.org/0000-0001-8775-0282

Funding

Jilin Province science and technology development plan project 20230204094YYNational Natural Science Foundation of China 82151318Science and Technology Commission of Shanghai 21Y11902500Science and Technology Commission of Shanghai 22DZ2229004Science and Technology Commission of Shanghai 22JC1403603Scientific Development funds for Local Region from the Chinese Government in 2023 XZ202301YD0032Cthe Key Research & Development Project of Zhejiang Province 2024C03240
6 · The paper itself

Abstract

Elevated intracranial pressure (ICP) is recognized as a biomarker of secondary brain injury, with a significant linear correlation observed between optic nerve sheath diameter (ONSD) and ICP. Frequent monitoring of ONSD could effectively support dynamic evaluation of ICP. However, ONSD measurement is heavily reliant on the operator's experience and skill, particularly in manually selecting the optimal frame from ultrasound sequences and measuring ONSD. This paper presents a novel method to automatically identify the optimal frame from video sequences for ONSD measurement by employing the kernel correlation filter (KCF) tracking algorithm and simple linear iterative clustering (SLIC) segmentation algorithm. The optic nerve sheath is mapped and measured using a Gaussian mixture model (GMM) combined with a KL divergence-based method. When compared with the average measurements of two expert clinicians, the proposed method achieved a mean error, mean squared deviation, and intraclass correlation coefficient (ICC) of 0.04, 0.054, and 0.782, respectively. The findings suggest that this method provides highly accurate automated ONSD measurements, showing potential for clinical application.

Indexed as

Optic NerveAdultAlgorithmsFemaleHumansImage Processing, Computer-AssistedIntracranial HypertensionIntracranial PressureMaleUltrasonographyVideo RecordingAutomated frame selectionIntracranial pressureOptic nerve sheath diameterUltrasound video analysis

Identifiers

PMID41087787

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.