Evidence map›Paper›PMID 41087747›Full record

ReviewAnalytical and bioanalytical chemistry2026

Smart microfluidic devices integrated in electrochemical point-of-care platforms for biomarker detection in biological fluids.

Vincenzo Mazzaracchio, Fabiana Arduini

Abstract readReview
In one paragraph

Review in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vincenzo MazzaracchioDepartment of Chemical Science and Technologies, University of Rome "Tor Vergata", Via Della Ricerca Scientifica 1, 00133, Rome, Italy. vincenzo.mazzaracchio@uniroma2.it.ORCID http://orcid.org/0000-0002-7851-4883
Fabiana ArduiniDepartment of Chemical Science and Technologies, University of Rome "Tor Vergata", Via Della Ricerca Scientifica 1, 00133, Rome, Italy.

Funding

Ministero dell'Università e della Ricerca (Italy) PRIN2022 project (2022XTCTWH-SMARTMASK4CF)
6 · The paper itself

Abstract

The increasing demand for decentralized, accessible, and rapid analytical tools is driving a transformation in healthcare toward point-of-care (POC) analytical technologies. The final aim is to reduce the cost of healthcare management originating from frequent patient hospitalizations and expensive and time-consuming laboratory-based analyses. This review explores the integration of microfluidic technologies with electrochemical sensing platforms, aiming to address the urgent need for POC analytical platforms. Owing to the miniaturization of fluid management systems and exploiting fluid automation, microfluidic devices enable low sample consumption, cost-effective analysis, and multiplexed detection, offering promising tools for real-time health monitoring. Among the other materials, the most commonly used substrates for microfluidics fabrication are paper, PDMS, and adhesive tape, which support custom-designed microchannel architectures, passive fluid motion, and wearable integration. Special attention is given to wearable sensors for sweat analysis, with various approaches employing capillary-driven flows and smart microfluidic designs to enable continuous and autonomous monitoring of biomarkers. Highlighting relevant works from the last 5 years, the review explores the role of integrated microfluidic electrochemical sensing devices in delivering advanced decentralized analytical platforms, with significant potential for clinical use in biomarker detection.

Indexed as

BiomarkersBody FluidsElectrochemical TechniquesLab-On-A-Chip DevicesMicrofluidic Analytical TechniquesPoint-of-Care SystemsBiosensing TechniquesEquipment DesignHumansBiomarkersBiomarker detectionElectrochemical sensingMicrofluidic technologiesPoint-of-care platformsWearable sensors

Identifiers

PMID41087747
PMCPMC12783325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.