Evidence map›Paper›PMID 41087644›Full record

ReviewLab animal2025

The role of the mycobiome in host physiology and disease: insights from rodent models.

Karen Antunes, Nathaniel B Willis, Joseph F Pierre

Abstract readReview
In one paragraph

Review in Lab animal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. International journal of molecular sciences · 2026
    Review
  3. Gut Microbiota and Metabolic Health: From Dysbiosis to Therapeutics.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karen Antunes *Department of Nutritional Sciences, College of Agriculture and Life Science, University of Wisconsin-Madison, Madison, WI, USA.
Nathaniel B Willis *Department of Nutritional Sciences, College of Agriculture and Life Science, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-1401-8204
Joseph F PierreDepartment of Nutritional Sciences, College of Agriculture and Life Science, University of Wisconsin-Madison, Madison, WI, USA. jpierre@wisc.edu.ORCID 0000-0002-4248-1290

Funding

TRAINING IN NUTRITIONT32DK007665 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI GUY E GROBLEWSKI, Chi- Liang Eric Yen · 1993 to 2026
$9.2M
Determining the contribution of microbial-derived metabolites to protective immunity in obesity-driven cancer risk.U01CA272541 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI Liza Makowski-Hayes, Joseph F PIERRE · 2022 to 2026
$5.1M
Exploring the role, regulation, and antimicrobial function of Paneth cell peptides PYY and NPY in maintaining gut microbial commensalism and innate immune defenseR01DK113788 · NIDDK · UNIVERSITY OF CHICAGO · PI EUGENE B CHANG, Joseph F PIERRE · 2017 to 2026
$4.6M
Role of microbial-modulated bile acid receptor signaling in breast cancerR01CA253329 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI Katherine Loree Cook, Liza Makowski-Hayes · 2020 to 2026
$3.0M
NCI NIH HHS R01 CA253329NCI NIH HHS U01 CA272541NIDDK NIH HHS R01 DK113788NIDDK NIH HHS T32 DK007665U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) NIH U01CA272541
6 · The paper itself

Abstract

Mammals have evolved under an inseparable association with diverse microbial gut colonizers; thus, fine-tuned host-microbial interactions shape our susceptibility to immunological, oncogenic, metabolic and infectious outcomes. The past two decades have seen a rapid expansion of research into intestinal bacterial communities that impact host health in many preclinical and clinical settings. Meanwhile, other less abundant microorganism domains, including fungi, remain far less explored. This Review provides an overview of the literature on the gut mycobiome and evidence of its contributions to host physiology and disease over the past two decades in experimental rodent models, which have been foundational to our current understanding of host-microbe interactions.

Indexed as

FungiGastrointestinal MicrobiomeHost Microbial InteractionsMycobiomeRodentiaAnimalsDisease Models, Animal

Identifiers

PMID41087644
PMCPMC12575366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.