Evidence map›Paper›PMID 41087556›Full record

ArticleScientific reports2025

Towards better illness perception in advanced chronic kidney disease: clinical, psychological and cognitive factors to address.

Alicia Tamarit, Laura Lacomba-Trejo, Eva Carbajo, Antonio Galán

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alicia TamaritDepartment of Social Psychology, Universitat de València, Valencia, Spain.
Laura Lacomba-TrejoDepartment of Evolutionary and Educational Psychology, Universitat de València, Valencia, Spain. laura.lacomba@uv.es.
Eva CarbajoClinical and Health Psychology Unit, Consorcio Hospital General Universitario de Valencia, Valencia, Spain.
Antonio GalánNephrology Department, Consorcio Hospital General de Valencia, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

People with advanced chronic kidney disease (ACKD) frequently experience psychological distress due to the progressive nature of the illness and the burden of long-term treatment. Illness perception plays a critical role in emotional adjustment and health behaviors, yet the psychosocial and clinical variables shaping these perceptions are not fully understood. This study aimed to identify combinations of psychological, behavioral, and clinical factors that predict how individuals with ACKD perceive their illness, using a Qualitative Comparative Analysis (QCA) approach. The sample included 69 participants with ACKD. Illness perception was assessed via the Brief Illness Perception Questionnaire (B-IPQ). Predictive conditions included: anxiety (HADS-A), coping styles (Brief COPE), kidney disease knowledge (KiKS), emotional social support (MOS-SSS), neuroticism (NEO-FFI), and CKD stage. QCA results revealed multiple pathways to high illness threat perception. Configurations characterized by high anxiety, elevated neuroticism, and low active coping were consistently associated with negative illness representations. Conversely, combinations including greater disease knowledge and active coping predicted more adaptive perceptions. These findings underscore the relevance of addressing both emotional and cognitive variables when designing psychosocial interventions for people with ACKD, supporting a multidimensional approach to improving patient adjustment and health outcomes.

Indexed as

CognitionRenal Insufficiency, ChronicAdaptation, PsychologicalAdultAgedAnxietyFemaleHumansMaleMiddle AgedNeuroticismPerceptionSocial SupportSurveys and QuestionnairesAnxietyChronic kidney diseaseCKD stageCoping strategiesHealth knowledgeIllness perceptionNeuroticism

Identifiers

PMID41087556
PMCPMC12521496

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.