Evidence map›Paper›PMID 41087458›Full record

ArticleScientific reports2025

Prehospital thrombolytic treatment of acute ischemic stroke using a remotely controlled CT scanner.

Susanne Gaarden Ingebrigtsen, Linn Hofsøy Steffensen, Kurt Bøckman Gschib, Øyvind Solbakken, Tor Ingebrigtsen, Ellisiv Bøgeberg Mathiesen, Agnethe Eltoft

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Susanne Gaarden IngebrigtsenDepartment of Neurology, University Hospital of North Norway, Tromsø, Norway.
Linn Hofsøy SteffensenDepartment of Neurology, University Hospital of North Norway, Tromsø, Norway.
Kurt Bøckman GschibDepartment of Radiology, University Hospital of North Norway, Tromsø, Norway.
Øyvind SolbakkenInformation and Technology Department, North Norway Health Trust, Tromsø, Norway.
Tor IngebrigtsenBrain and Circulation Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
Ellisiv Bøgeberg MathiesenDepartment of Neurology, University Hospital of North Norway, Tromsø, Norway.
Agnethe EltoftDepartment of Neurology, University Hospital of North Norway, Tromsø, Norway. agnethe.eltoft@uit.no.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Timely access to diagnosis and treatment is crucial for improving stroke patients´ outcomes, but long prehospital transport times hinder timely treatment in rural areas. This study investigates the feasibility of using a remotely controlled computer tomography (CT) scanner at a decentralized medical center (DMC) to expedite prehospital intravenous thrombolysis (IVT) for acute ischemic stroke (AIS). The study involved three phases: technical implementation and testing, procedure development, and clinical training. We used a Siemens Healthineers Syngo Virtual Cockpit system to remotely control the CT scanner at the DMC. This enabled use of the scanner without a radiographer on call at the DMC. Eligibility criteria for undergoing prehospital IVT at the DMC were established. Paramedics, nurses, and physicians underwent comprehensive training on stroke assessment, CT scanner operation, and communication protocols. Technical testing demonstrated excellent feasibility of the system. Simulation exercises showed efficient teamwork, achievement of door-to-needle times (DNT) below 20 min, and NIHSS score consistency in 95% of cases. Risk assessment identified potential challenges, with mitigation strategies implemented. This study demonstrates the feasibility of leveraging existing infrastructure to remotely control a CT scanner at a DMC, for prehospital IVT in a rural setting. This approach is promising for improving timely stroke diagnosis and treatment in rural areas.

Indexed as

Emergency Medical ServicesIschemic StrokeThrombolytic TherapyTomography Scanners, X-Ray ComputedTomography, X-Ray ComputedAgedFemaleHumansMaleTime-to-Treatment

Identifiers

PMID41087458
PMCPMC12521348

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.