ArticleScientific reports2025
Genetic isolation drives divergent insecticide resistance between coastal and western Kenya Anopheles funestus populations.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Signature of resistance gene evolution and pyrethroid resistance escalation in the major malaria vector Anopheles funestus across Kenyan malaria-endemic regions separated by the Rift Valley.Infectious diseases of poverty · 2026Article
- Genomic signatures of selection inbioRxiv : the preprint server for biology · 2026Article
- Genetic diversity and gut microbiome of Anopheles mosquitoes in Tamil Nadu by using COI DNA barcoding and 16S rRNA metagenomics.Scientific reports · 2026Article
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15 authors.
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Abstract
Escalating levels of insecticide resistance and adaptive changes in mosquito populations threaten recent gains in malaria control. Understanding the molecular, ecological, and evolutionary processes driving these transformations is important for extending the effectiveness of current insecticides and informing the development of effective strategies and tools for vector control and insecticide resistance management. This study analyzed 103 whole-genome sequences from Anopheles funestus s.s. mosquitoes collected before the implementation of non-pyrethroid-based vector control tools in Kenya in 2017. Mosquito samples were collected from the western Kenya region (Bungoma, Migori and Kisumu Counties), the region with the highest malaria prevalence and the coastal region (Kilifi County), which has the second-highest malaria prevalence in Kenya. The study determined the population structure, evaluated the presence of insecticide-resistant alleles associated with pyrethroid insecticides and identified patterns of gene flow. Based on our results, Anopheles funestus s.s. from the western Kenya region were highly differentiated from the coastal population with a mean F
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