Evidence map›Paper›PMID 41087362›Full record

ArticleNPJ primary care respiratory medicine2025

De-implementation of inappropriate inhaled corticosteroid use in patients with COPD in general practice, results of a mixed methods study.

Lisette van den Bemt, Bert van Bremen, Janet de Boer, Agnes Poelman, Joke Grootens, Erik Bischoff, Tijn Kool, Tjard Schermer

Abstract read
In one paragraph

Article in NPJ primary care respiratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lisette van den BemtDepartment of Primary and Community Care, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. Lisette.vandenbemt@radboudumc.nl.
Bert van BremenGP with extra role asthma COPD. regional general practices cooperation Dokter Drenthe, Stationsstraat 44, 9401 KX, Assen, The Netherlands.
Janet de BoerCoordinator integrated care. Regional general practices cooperation Dokter Drenthe, Stationsstraat 44, 9401 KX, Assen, The Netherlands.
Agnes PoelmanCoordinator elderly Care. regional general practices cooperation Dokter Drenthe, Stationsstraat 44, 9401 KX, Assen, The Netherlands.
Joke GrootensDepartment of Primary and Community Care, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Erik BischoffDepartment of Primary and Community Care, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Tijn KoolIQ Health science department, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Tjard SchermerDepartment of Primary and Community Care, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many patients with COPD use inhaled corticosteroids (ICS) without proper indication. We developed a multifaceted tailor-made de-implementation strategy-including a toolbox, communication plan, and training-to reduce inappropriate ICS use in general practice. We evaluated its effectiveness (i.e. decline in percentage of patients with COPD that use ICS) and other outcomes during a 15-month study in Drenthe, the Netherlands. Less patients (-4.7%,95%CI: 2.6-6.7%) used ICS at the end of follow-up and the percentage of ICS-users declined by 8.2% (95%CI: 2.9-13.4%) across the 14 practices that fully participated in the project. ICS user percentages declined significantly moreover time in the fully participation group than in the control group (beta-regression, β = -0.041,SE = 0.011, p < 0.01). While these findings are promising, further research is needed to assess additional penetration and sustainability of the strategy in the region and to explore the applicability of comparable regional ICS de-implementation plans.

Indexed as

Adrenal Cortex HormonesGeneral PracticeInappropriate PrescribingPulmonary Disease, Chronic ObstructiveAdministration, InhalationAgedFemaleHumansMaleMiddle AgedNetherlandsAdrenal Cortex Hormones

Identifiers

PMID41087362
PMCPMC12521381

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.